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Acute Phase Response-driven Hepatic Niche Remodeling Promotes Fibrosis Resolution After Alcohol Cessation. [PDF]

open access: yesCell Mol Gastroenterol Hepatol
Schonfeld M   +5 more
europepmc   +1 more source

Liver regeneration: unraveling the molecular mechanisms and clinical application. [PDF]

open access: yesJ Transl Med
Wang N   +6 more
europepmc   +1 more source
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Hepatocyte Couplets

Biochemical Society Transactions, 2000
Hepatocyte couplets, by retaining functional and morphological polarity similar to that of hepatocytes in situ, are a valuable in vitro model to study mechanisms of bile secretion, cholestasis and hepatocellular injury. They have been useful in studies of the hormonal control of bile formation and are suitable for morphological studies.
R, Coleman, M G, Roma
openaire   +2 more sources

Hepatocyte Polarity

Comprehensive Physiology, 2013
AbstractHepatocytes, like other epithelia, are situated at the interface between the organism's exterior and the underlying internal milieu and organize the vectorial exchange of macromolecules between these two spaces. To mediate this function, epithelial cells, including hepatocytes, are polarized with distinct luminal domains that are separated by ...
Aleksandr, Treyer, Anne, Müsch
openaire   +2 more sources

Long-term functional maintenance of primary human hepatocytes in vitro

Science, 2019
Keep hepatocytes fresh Freshly isolated primary human hepatocytes (PHHs) quickly lose their identity and function in vitro, limiting their application in modeling infectious liver diseases and screening drugs. Xiang et al. describe a simple and effective
Chengang Xiang   +26 more
semanticscholar   +1 more source

Hepatocyte Xenotransplantation

2012
Xenotransplantation of hepatocytes is a future promise to treat liver diseases when there is a formal indication for transplantation. In this chapter, we describe techniques for hepatocyte xenotransplantation. The process was divided into three main steps: hepatocyte isolation, transplantation, and identification of donor cells in the recipient.
Katia R F, Lima-Quaresma   +4 more
openaire   +2 more sources

Microencapsulating Hepatocytes

Transplantation Proceedings, 2005
Because standardization of the cell microencapsulation procedure has not yet been achieved, we performed hepatocyte microencapsulation using alginate (ALG)-poly-l-lysine (PLL)-ALG (APA) polymer.Hepatocytes were microencapsulated using a binozzle air-jet droplet generator.
Y, Gao   +4 more
openaire   +2 more sources

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