Results 31 to 40 of about 242,511 (240)

Liver Disease Associated with Inflammatory Bowel Disease

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Inflammatory Bowel Disease (IBD) is a chronic condition characterized by persistent inflammation of the gastrointestinal tract, comprising ulcerative colitis (UC) and Crohn’s disease (CD). While the current global incidence of IBD exceeds 0.3% in Western
Juferdy Kurniawan, Refael Alfa Budiman
doaj   +1 more source

Clinical Practice Guideline for the Diagnosis and Treatment of Pediatric Obesity: Recommendations from the Committee on Pediatric Obesity of the Korean Society of Pediatric Gastroenterology Hepatology and Nutrition [PDF]

, 2019
The Committee on Pediatric Obesity of the Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition newly developed the first Korean Guideline on the Diagnosis and Treatment of Obesity in Children and Adolescents to deliver an evidence-based
고홍
core   +1 more source

Liver Is the Major Source of Elevated Serum Lipocalin-2 Levels After Bacterial Infection or Partial Hepatectomy: A Critical Role for IL-6/STAT3

, 2015
Lipocalin-2 (LCN2) was originally isolated from human neutrophils and termed neutrophil gelatinase-associated lipocalin (NGAL). However, the functions of LCN2 and the cell types that are primarily responsible for LCN2 production remain unclear.
Cowland, Jack B, Xu, Ming-Jiang, Wu, Hailong, Berger, Thorsten, Xu, Ming Jiang, Porse, Bo, Gao, Bin, Feng, Dechun, Kong, Xiaoni, Chan, Yvonne, Kolls, Jay, Mak, Tak W., Cowland, Jack B., Mak, Tak W, Wang, Hua, Borregaard, Niels   +15 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

EMERGING THERAPIES IN PRIMARY BILIARY CHOLANGITIS: OVERVIEW OF CLINICALTRIALS.GOV [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Background: Primary biliary cholangitis (PBC) is an autoimmune disorder leading to different hepatic disorders. Progressive bile duct damage could result in cirrhosis.
Nasser Alorfi, Mansour Alourfi, Saeed Alsharif, Mohannad Aljehani, Abdulmalik Alsabban, Mohammad Almatrafi, Ysear Zakri, Abdullah AlMahmoud, Monther Ghunaiem, Rami Almalki, Ibrahim Aljerary, Abdullah Alkhattabi   +11 more
doaj   +1 more source

Imaging of chemotherapy-induced liver toxicity: an illustrated overview

Hepatic Oncology, 2021
Chemotherapy is a potential cause of focal and diffuse hepatobiliary lesions. Many of these lesions may be demonstrated on imaging, especially computed tomography and MRI.
Giovanni Brondani Torri, Matheus Dorigatti Soldatelli, Gustavo Felipe Luersen, Caroline Lorenzoni Almeida Ghezzi   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

THE ROLE OF DIGESTIVE MANIFESTATIONS IN COVID-19 MORTALITY: EVIDENCES FROM BRAZIL’S FIRST EPIDEMIC WAVE [PDF]

Arquivos de Gastroenterologia
Context: COVID-19, caused by SARS-CoV-2, is primarily characterized by respiratory symptoms but also significantly affects the gastrointestinal (GI) tract and liver.
Elvis Paim FERREIRA, Mariana da Silva ARBUÉS, André Castro LYRA, Lourianne Nascimento CAVALCANTE   +3 more
doaj   +1 more source

Soaring rates of alcohol‐related hepatitis in the latter phase of the COVID‐19 pandemic: A new normal?

JGH Open, 2023
Background Studies have reported that the COVID‐19 pandemic has led to an increase in alcohol consumption and alcohol‐associated health problems in the general population.
Aalam Sohal, Sameeha Khalid, Victoria Green, Jeffrey Hagino, Hunza Chaudhry, Alakh Gulati, Marina Roytman   +6 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source