Results 21 to 30 of about 183,501 (239)

Predisposing and precipitating risk factors for delirium in gastroenterology and hepatology: Subgroup analysis of 718 patients from a hospital-wide prospective cohort study

Frontiers in Medicine, 2022
Background and AimsDelirium is the most common acute neuropsychiatric syndrome in hospitalized patients. Higher age and cognitive impairment are known predisposing risk factors in general hospital populations.
Florian F. Hildenbrand, Florian F. Hildenbrand, Fritz R. Murray, Fritz R. Murray, Roland von Känel, Ansgar R. Deibel, Philipp Schreiner, Jutta Ernst, Carl M. Zipser, Carl M. Zipser, Soenke Böettger   +10 more
doaj   +1 more source

The evolution of artificial intelligence technology in non-alcoholic fatty liver disease

Frontiers in Radiology
BackgroundThe incidence of Non-alcoholic Fatty Liver Disease (NAFLD) continues to rise, becoming one of the major causes of chronic liver disease globally and posing significant challenges to healthcare systems worldwide.
Jiawen He, Yao Wu, Zhiyong Lin, Ruohong He, Li Zhuo, Yingying Li   +5 more
doaj   +1 more source

Imaging of chemotherapy-induced liver toxicity: an illustrated overview

Hepatic Oncology, 2021
Chemotherapy is a potential cause of focal and diffuse hepatobiliary lesions. Many of these lesions may be demonstrated on imaging, especially computed tomography and MRI.
Giovanni Brondani Torri, Matheus Dorigatti Soldatelli, Gustavo Felipe Luersen, Caroline Lorenzoni Almeida Ghezzi   +3 more
doaj   +1 more source

Applications of Artificial Intelligence in Alpha-1 Antitrypsin Deficiency: A Systematic Review from a Respiratory Medicine Perspective

Medicina
Background and Objectives: Alpha-1 antitrypsin deficiency (AATD) is a rare genetic condition associated with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) and emphysema, and with liver involvement through a distinct ...
Manuel Casal-Guisande, Laura Villar-Aguilar, Alberto Fernández-Villar, Esmeralda García-Rodríguez, Ana Casal, María Torres-Durán   +5 more
doaj   +1 more source

Soaring rates of alcohol‐related hepatitis in the latter phase of the COVID‐19 pandemic: A new normal?

JGH Open, 2023
Background Studies have reported that the COVID‐19 pandemic has led to an increase in alcohol consumption and alcohol‐associated health problems in the general population.
Aalam Sohal, Sameeha Khalid, Victoria Green, Jeffrey Hagino, Hunza Chaudhry, Alakh Gulati, Marina Roytman   +6 more
doaj   +1 more source

Liver Disease Associated with Inflammatory Bowel Disease

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Inflammatory Bowel Disease (IBD) is a chronic condition characterized by persistent inflammation of the gastrointestinal tract, comprising ulcerative colitis (UC) and Crohn’s disease (CD). While the current global incidence of IBD exceeds 0.3% in Western
Juferdy Kurniawan, Refael Alfa Budiman
doaj   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

THE ROLE OF DIGESTIVE MANIFESTATIONS IN COVID-19 MORTALITY: EVIDENCES FROM BRAZIL’S FIRST EPIDEMIC WAVE [PDF]

Arquivos de Gastroenterologia
Context: COVID-19, caused by SARS-CoV-2, is primarily characterized by respiratory symptoms but also significantly affects the gastrointestinal (GI) tract and liver.
Elvis Paim FERREIRA, Mariana da Silva ARBUÉS, André Castro LYRA, Lourianne Nascimento CAVALCANTE   +3 more
doaj   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source