Results 41 to 50 of about 229,729 (307)

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

eLife, 2019
Recent studies have identified a genetic variant rs641738 near two genes encoding membrane bound O-acyltransferase domain-containing 7 (MBOAT7) and transmembrane channel-like 4 (TMC4) that associate with increased risk of non-alcoholic fatty liver ...
Robert N Helsley, Venkateshwari Varadharajan, Amanda L Brown, Anthony D Gromovsky, Rebecca C Schugar, Iyappan Ramachandiran, Kevin Fung, Mohammad Nasser Kabbany, Rakhee Banerjee, Chase K Neumann, Chelsea Finney, Preeti Pathak, Danny Orabi, Lucas J Osborn, William Massey, Renliang Zhang, Anagha Kadam, Brian E Sansbury, Calvin Pan, Jessica Sacks, Richard G Lee, Rosanne M Crooke, Mark J Graham, Madeleine E Lemieux, Valentin Gogonea, John P Kirwan, Daniela S Allende, Mete Civelek, Paul L Fox, Lawrence L Rudel, Aldons J Lusis, Matthew Spite, J Mark Brown   +32 more
doaj   +1 more source

Alpha‐fetoprotein and focal nodular hyperplasia: An unconventional couple

JGH Open, 2021
We report the case of a 36‐year‐old patient who was initially managed for gynecomastia. The first biological analyses showed a moderately elevated alpha‐fetoprotein (AFP) level.
Paul Carrier, Anne Guyot, Marilyne Debette‐Gratien, Fabien Fredon, Marie‐Pierre Teissier, François Labrousse, Véronique Loustaud‐Ratti   +6 more
doaj   +1 more source

Expanding Pharmacists’ Role in the Management of Non-Alcoholic Fatty Liver Disease

Pharmacy, 2023
Non-alcoholic fatty liver disease (NAFLD) stands as an increasingly pressing global health challenge, underscoring the need for timely identification to facilitate effective treatment and prevent the progression of chronic liver disorders.
Majid Mufaqam Syed-Abdul
doaj   +1 more source

The evolution of artificial intelligence technology in non-alcoholic fatty liver disease

Frontiers in Radiology
BackgroundThe incidence of Non-alcoholic Fatty Liver Disease (NAFLD) continues to rise, becoming one of the major causes of chronic liver disease globally and posing significant challenges to healthcare systems worldwide.
Jiawen He, Yao Wu, Zhiyong Lin, Ruohong He, Li Zhuo, Yingying Li   +5 more
doaj   +1 more source

Applications of Artificial Intelligence in Alpha-1 Antitrypsin Deficiency: A Systematic Review from a Respiratory Medicine Perspective

Medicina
Background and Objectives: Alpha-1 antitrypsin deficiency (AATD) is a rare genetic condition associated with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) and emphysema, and with liver involvement through a distinct ...
Manuel Casal-Guisande, Laura Villar-Aguilar, Alberto Fernández-Villar, Esmeralda García-Rodríguez, Ana Casal, María Torres-Durán   +5 more
doaj   +1 more source

Predisposing and precipitating risk factors for delirium in gastroenterology and hepatology: Subgroup analysis of 718 patients from a hospital-wide prospective cohort study

Frontiers in Medicine, 2022
Background and AimsDelirium is the most common acute neuropsychiatric syndrome in hospitalized patients. Higher age and cognitive impairment are known predisposing risk factors in general hospital populations.
Florian F. Hildenbrand, Florian F. Hildenbrand, Fritz R. Murray, Fritz R. Murray, Roland von Känel, Ansgar R. Deibel, Philipp Schreiner, Jutta Ernst, Carl M. Zipser, Carl M. Zipser, Soenke Böettger   +10 more
doaj   +1 more source

Hepatology Highlights [PDF]

, 2013
In this issue of the Annals of Hepatology the readers are invited to look closely at four articles from four different continents all of which are attempting to identify clinical predictors to facilitate management of patients with liver disease and ...
Kevork M. Peltekian, M.D.
core   +1 more source

Liver Disease Associated with Inflammatory Bowel Disease

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Inflammatory Bowel Disease (IBD) is a chronic condition characterized by persistent inflammation of the gastrointestinal tract, comprising ulcerative colitis (UC) and Crohn’s disease (CD). While the current global incidence of IBD exceeds 0.3% in Western
Juferdy Kurniawan, Refael Alfa Budiman
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

EMERGING THERAPIES IN PRIMARY BILIARY CHOLANGITIS: OVERVIEW OF CLINICALTRIALS.GOV [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Background: Primary biliary cholangitis (PBC) is an autoimmune disorder leading to different hepatic disorders. Progressive bile duct damage could result in cirrhosis.
Nasser Alorfi, Mansour Alourfi, Saeed Alsharif, Mohannad Aljehani, Abdulmalik Alsabban, Mohammad Almatrafi, Ysear Zakri, Abdullah AlMahmoud, Monther Ghunaiem, Rami Almalki, Ibrahim Aljerary, Abdullah Alkhattabi   +11 more
doaj   +1 more source