Results 121 to 130 of about 84,845 (281)

Dual Monogenic Cystic Disease Case Report: Autosomal Dominant Polycystic Kidney Disease and Autosomal Dominant Polycystic Liver Disease [PDF]

Clin Case Rep
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses. Here, we report a case of a 50‐year‐old woman with a clinical diagnosis of ADPKD, hypertension, preserved kidney function ...
Brossart A, Curry K, Punj S, Darwish T, Tabriziani H.   +4 more
europepmc   +2 more sources

Prevalence and Diagnostic Challenge of Hemophagocytic Lymphohistiocytosis Syndrome in Critically Ill Patients

European Journal of Haematology, EarlyView.
ABSTRACT Background Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is a severe condition with a challenging diagnosis in the intensive care unit (ICU), for which current recommendations rely on fulfilling five of eight HLH‐2004 criteria.
Claire Queffeulou, Mathieu Bellal, Suzanne Goursaud, Sylvain Chantepie, Damien du Cheyron   +4 more
wiley   +1 more source

Advanced Ultrasound Workshops for Emergency Medicine Residents

Journal of Education and Teaching in Emergency Medicine, 2017
Audience and type of curriculum: This ultrasound curriculum is designed for second-year emergency medicine residents who have completed a 2-week dedicated ultrasound rotation covering the American College of Emergency Physicians (ACEP) core applications.
Michelle Lall, Sierra Beck, Jehangir Meer   +2 more
doaj   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Intratumoral chemotherapy in an integumentary squamous cell carcinoma in a cockatiel (Nymphicus hollandicus) [PDF]

, 2018
An eight-year-old, female cockatiel (Nymphicus hollandicus) was presented with anorexia, lethargy, a mass at the lower side of the wing and discoloration of the feathers.
Antonissen, Gunther, Croubels, Siska, Ducatelle, Richard, Garmyn, An, Hellebuyck, Tom, Martel, An, Van de Maele, Isabel, Van Hecke, Naomi   +7 more
core  

First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing

Journal of Fish Biology, EarlyView.
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley   +1 more source

Efficacy of Ultrasound for the Detection of Possible Fatty Liver Disease in Children

Diagnostics
Pediatric MASLD (previously referred to as NAFLD) incidence has continued to rise along with the obesity pandemic. Pediatric MASLD increases the risk of liver fibrosis and cirrhosis in adulthood.
Sarah B. Lowry, Shelly Joseph, Kevin J. Psoter, Emily Dunn, Sana Mansoor, S. Kathryn Smith, Wikrom Karnsakul, Gihan Naguib, Kenneth Ng, Ann O. Scheimann   +9 more
doaj   +1 more source

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.

Genes & Development, 2012
The Drosophila TEAD ortholog Scalloped is required for Yki-mediated overgrowth but is largely dispensable for normal tissue growth, suggesting that its mammalian counterpart may be exploited for selective inhibition of oncogenic growth driven by YAP ...
Y. Liu-Chittenden, Bo Huang, J. Shim, Qian Chen, Se-Jin Lee, R. Anders, Jun O. Liu, D. Pan   +7 more
semanticscholar   +1 more source

Bath Treatments With Emamectin Benzoate Control Dactylogyrideans Infecting Colossoma macropomum Gills Without Altering Physiology of This Host Fish

Journal of Fish Diseases, EarlyView.
ABSTRACT Intensification of fish aquaculture worldwide has led to severe problems of diseases caused by parasitic dactylogyrideans. In this study, the anti‐dactylogyridean efficacy of treating Colossoma macropomum with baths of emamectin benzoate (EMB) was investigated for the first time, along with the effects of this treatment on the haematology and ...
Raimundo Rosemiro de Jesus Baia, Marcela Nunes Videira, Amanda Mendes Pacheco, Eliane Tie Oba Yoshioka, Marcos Tavares‐Dias   +4 more
wiley   +1 more source