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Hepatoprotective natural triterpenoids

European Journal of Medicinal Chemistry, 2018
Liver diseases are one of the leading causes of death in the world. In spite of tremendous advances in modern drug research, effective and safe hepatoprotective agents are still in urgent demand. Natural products are undoubtedly valuable sources for drug leads.
Guo-Bo, Xu   +4 more
openaire   +2 more sources

Hepatoprotective functions of jujuboside B

Journal of Natural Medicines, 2022
Jujuboside B (JB) found in the seeds of Zizyphi Spinosi Semen possesses pharmacological functions, such as anti-inflammatory, antiplatelet aggregation, and antianxiety potentials. This study evaluated the effect of JB on liver failure in cecal ligation and puncture (CLP)-induced sepsis.
Chaeyeong Kim   +4 more
openaire   +2 more sources

Hepatoprotective constituents ofcudrania tricuspidata

Archives of Pharmacal Research, 2005
Phytochemical investigation of the MeOH extract of the root barks of Cudrania tricuspidata Bureau (Moraceae), as guided by hepatoprotective activity in vitro, furnished four isoprenylated xanthones, cudratricusxanthone A (1), cudraxanthone L (2), cudratricusxanthone E (3), and macluraxanthone B (4).
Yu-Hua, Tian   +3 more
openaire   +2 more sources

Hepatoprotective effects of Astraglus root

Journal of Ethnopharmacology, 1990
Oral administration of an ethanol extract of the root of Astragalus membranaceus alleviated liver injury induced by stilbenemidine. Pre-administration in mice reduced elevated SGPT levels and subacute toxicity of stilbenemidine, decreased pentobarbital-induced loss of righting reflex and protected hepatic cells from pathological changes.
Z L, Zhang, Q Z, Wen, C X, Liu
openaire   +2 more sources

Present status of hepatoprotectants

1999
Perpetual exposure of liver to xenobiotics and therapeutic agents leads to toxic manifestations of a complex and diverse nature. Not a single curative therapeutic agent has been found so far which could provide lasting remedy to patients suffering from hepatic disorders.
V J, Ram, A, Goel
openaire   +2 more sources

A systematic review on hepatoprotective activity of quercetin against various drugs and toxic agents: Evidence from preclinical studies

Phytotherapy Research, 2019
Quercetin is one of the most abundant flavonoids in human diet that has been reported to exhibit a wide range of pharmacological properties. The biochemical and molecular mechanisms involved in the hepatoprotective activity of quercetin were discussed in
Ravindrababu Pingili   +5 more
semanticscholar   +1 more source

Mechanisms of Tauroursodeoxycholate-Mediated Hepatoprotection

Digestive Diseases, 2017
Ursodeoxycholate and its taurine conjugate tauroursodeoxycholate (TUDC) promote choleresis by triggering the insertion of transport proteins for bile acids into the canalicular and basolateral membranes of hepatocytes. In addition, TUDC exerts hepatoprotective and anti-apoptotic effects, can counteract the action of toxic bile acids and reduce ...
Dieter, Häussinger, Claus, Kordes
openaire   +2 more sources

Tunisian Hepatoprotective Plants

2018
Purpose: Liver diseases are an important health problem in Tunisia where the use of the medicinal plants in liver protection is very popular. Many previous studies showed that a wide range of Tunisian medicinal plants had hepatoprotective activity. Methods: A comprehensive review was conducted to a mass data from scientific researches about Tunisian ...
Aidi Wannes Wissem   +2 more
openaire   +1 more source

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