Results 131 to 140 of about 146,077 (348)

Uncovering the Mechanism of Hepatotoxiciy of PFAS Targeting L-FABP Using GCN and Computational Modeling [PDF]

arXiv
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with known toxicity and bioaccumulation issues. Their widespread industrial use and resistance to degradation have led to global environmental contamination and significant health concerns. While a minority of PFAS have been extensively studied, the toxicity of many PFAS
arxiv  

Hepatotoxicity in patients with non-small cell lung cancer treated with sotorasib after prior immunotherapy: a comprehensive clinical and pharmacokinetic analysisResearch in context

EBioMedicine
Summary: Background: Sotorasib given after immunotherapy could put patients at increased risk of hepatotoxicity. Therefore, there is a need to gain insight into the potential correlation between anti-PD-(L)1 treatment, anti-PD-(L)1 concentrations ...
Sophie M. Ernst, Maaike M. Hofman, Tessa E. van der Horst, Marthe S. Paats, Frank W.J. Heijboer, Joachim G.J.V. Aerts, Daphne W. Dumoulin, Robin Cornelissen, Jan H. von der Thüsen, Peter de Bruijn, Esther Oomen-de Hoop, Ron H.J. Mathijssen, Stijn L.W. Koolen, Anne-Marie C. Dingemans   +13 more
doaj  

Explainable Molecular Property Prediction: Aligning Chemical Concepts with Predictions via Language Models [PDF]

arXiv
Providing explainable molecular property predictions is critical for many scientific domains, such as drug discovery and material science. Though transformer-based language models have shown great potential in accurate molecular property prediction, they neither provide chemically meaningful explanations nor faithfully reveal the molecular structure ...
arxiv  

Foetal and neonatal responses to hepatotoxic agents [PDF]

, 1965
Kallol Kumar Bhattacharyya
openalex   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, EarlyView., 2023
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12) [PDF]

, 2015
Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Abbasi, A., Ghasemi Kebria, F., Hashemi Fard, A., Khodabakhshi, B., Khosravian, M.   +4 more
core  

The protective effect of nicotinamide on carbon tetrachloride-induced hepatotoxicity [PDF]

, 1967
James W. Gibb, Thomas Brody
openalex   +1 more source

Is ALT control really necessary for routine ART monitoring in resource poor settings? [PDF]

, 2006
2006 AIDS Conference in ...
di Mattei, P, Gregorio, D, Nguimfack, A, Sitoe, F, Toalha, B   +4 more
core   +1 more source

SOME ASPECTS OF EXPERIMENTAL CARBON TETRA‐CHLORIDE‐INDUCED HEPATOTOXICITY* [PDF]

, 1963
Theodore M. Brody
openalex   +1 more source

Perampanel monotherapy in pediatric epilepsy: Emphasizing the need for comprehensive safety evaluation

Epilepsia Open, EarlyView.
Gabriel Christian de Farias Morais, Guilherme Bastos Alves, Shahina Akter, Shopnil Akash, Md. Aktaruzzaman, Md. Sakib Al Hasan, Umberto Laino Fulco, Edilson Dantas da Silva Junior, Jonas Ivan Nobre Oliveira   +8 more
wiley   +1 more source