Results 131 to 140 of about 160,647 (335)

Hepatotoxicity

open access: yesFolia Pharmacologica Japonica, 2008
Munehiro, Teranishi, Sunao, Manabe
openaire   +3 more sources

Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing was performed on tumor tissues from triptolide‐treated tumor‐bearing mice. The sequencing results were integrated with data from public databases for comprehensive analysis, and potential regulatory targets of triptolide were identified.
Zhiwen Cao   +12 more
wiley   +1 more source

The Influence of Safety, Efficacy, and Medical Condition Severity on Natural v. Synthetic Drug Preference

open access: yes, 2016
Research indicates that there is a preference for natural v. synthetic products, but the influence of this preference on drug choice in the medical domain is largely unknown.
Lappas, Courtney M., Meier, Brian P.
core   +1 more source

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Effects of <i>Euphorbia thymifolia</i> and <i>Euphorbia hirta</i> leaf extracts on membrane-bound, mitochondrial enzymes and lipid profile of carbon tetrachloride-induced hepatotoxicity in rats [PDF]

open access: bronze, 2022
Gurupalraj Durai Muthu Mani   +7 more
openalex   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Lactobacillus rhamnosus GG ameliorates triptolide-induced liver injury through modulation of the bile acid-FXR axis

open access: yesPharmacological Research
Triptolide (TP) is the principal bioactive compound of Tripterygium wilfordii with significant anti-tumor, anti-inflammatory and immunosuppressive activities. However, its severe hepatotoxicity greatly limits its clinical use. The underlying mechanism of
Shiping Hu   +9 more
doaj   +1 more source

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