Results 211 to 220 of about 79,419 (267)
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Hepatotoxicity of chemotherapy
Expert Opinion on Drug Safety, 2002The selection of a chemotherapeutic regimen for the oncology patient is based on a thorough assessment of potential hazards relating to the patient's clinical condition and the toxicities of chemotherapy. Liver function abnormalities are commonly seen in this patient population and deducing their aetiology may be difficult.
Bradley, Sachs +4 more
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The Journal of Urology, 1996
Observed and expected reporting rates were compared in patients who died or were hospitalized due to hepatotoxicity associated with the use of flutamide.Case series were submitted to the MedWatch Spontaneous Reporting System of the Food and Drug Administration.
D K, Wysowski, J L, Fourcroy
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Observed and expected reporting rates were compared in patients who died or were hospitalized due to hepatotoxicity associated with the use of flutamide.Case series were submitted to the MedWatch Spontaneous Reporting System of the Food and Drug Administration.
D K, Wysowski, J L, Fourcroy
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Gastroenterology, 1980
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
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This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
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Hepatotoxicity of Antidepressants
International Clinical Psychopharmacology, 1991Detection of abnormal liver function tests in a patient receiving an antidepressant or other psychopharmacological agent presents a major problem to the clinician, who must decide whether or not to withdraw a drug which may be of central importance in the patient's management.
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Hepatotoxicity of Mercaptopurine
JAMA, 1964In a study of 49 leukemic patients, jaundice occurred in 16 of 38 who were treated with mercaptopurine (6-mercaptopurine), but only in one of 11 not receiving the drug. In eight patients jaundice cleared up rapidly on cessation of mercaptopurine therapy, and there was a recurrence of jaundice in two who were rechallenged with the drug.
M, EINHORN, I, DAVIDSOHN
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American Journal of Health-System Pharmacy, 1978
A case of aspirin hepatotoxicity in a 46-year-old male with rheumatoid arthritis is discussed, and this adverse reaction is reviewed. The patient was started on 900 mg aspirin four times daily; five days later the dose was increased to 1200 mg four times daily. After six days' therapy of 4.8 g aspirin daily, the serum salicylate level rose to 25 mg/100
S A, Kanada, W M, Kolling, B I, Hindin
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A case of aspirin hepatotoxicity in a 46-year-old male with rheumatoid arthritis is discussed, and this adverse reaction is reviewed. The patient was started on 900 mg aspirin four times daily; five days later the dose was increased to 1200 mg four times daily. After six days' therapy of 4.8 g aspirin daily, the serum salicylate level rose to 25 mg/100
S A, Kanada, W M, Kolling, B I, Hindin
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Clinics in Liver Disease, 2007
Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The initial metabolic and biochemical events leading to toxicity have been well described, but the precise mechanism of cell injury and death is unknown. Prompt recognition of
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Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The initial metabolic and biochemical events leading to toxicity have been well described, but the precise mechanism of cell injury and death is unknown. Prompt recognition of
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Journal of Clinical Psychopharmacology, 1997
Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
M, Hummer +5 more
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Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
M, Hummer +5 more
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Annals of Internal Medicine, 1979
Excerpt To the editor: The report of Onorata and Axelrod in the October issue (1) emphasizes the otherwise poorly recognized risk of hepatotoxicity from high-dose intravenous oxacillin.
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Excerpt To the editor: The report of Onorata and Axelrod in the October issue (1) emphasizes the otherwise poorly recognized risk of hepatotoxicity from high-dose intravenous oxacillin.
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Hepatotoxicity of thiazolidinediones
Expert Opinion on Drug Safety, 2003Thiazolidinediones are insulin sensitisers now widely used for the treatment of Type 2 diabetes mellitus. The initial marketed drug in this class, troglitazone, was removed from the market worldwide after approximately 3 years of use due to rare but severe hepatotoxicity, which sometimes resulted in liver failure leading to the need for liver ...
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