Results 301 to 310 of about 137,616 (341)
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Annals of Internal Medicine, 1979
Excerpt To the editor: The report of Onorata and Axelrod in the October issue (1) emphasizes the otherwise poorly recognized risk of hepatotoxicity from high-dose intravenous oxacillin.
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Excerpt To the editor: The report of Onorata and Axelrod in the October issue (1) emphasizes the otherwise poorly recognized risk of hepatotoxicity from high-dose intravenous oxacillin.
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The Journal of Urology, 1996
Observed and expected reporting rates were compared in patients who died or were hospitalized due to hepatotoxicity associated with the use of flutamide.Case series were submitted to the MedWatch Spontaneous Reporting System of the Food and Drug Administration.
D K, Wysowski, J L, Fourcroy
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Observed and expected reporting rates were compared in patients who died or were hospitalized due to hepatotoxicity associated with the use of flutamide.Case series were submitted to the MedWatch Spontaneous Reporting System of the Food and Drug Administration.
D K, Wysowski, J L, Fourcroy
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Analysis of Risk Factors for Hepatotoxicity Induced by Immune Checkpoint Inhibitors
Journal of immunotherapy, 2020Supplemental Digital Content is available in the text. Although hepatotoxicity induced by immune checkpoint inhibitors (ICPIs) can cause severe clinical complications, the risk factors associated with hepatotoxicity have rarely been investigated.
Young-ah Cho +6 more
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Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors.
American Journal of Gastroenterology, 2019INTRODUCTION We conducted this study to characterize the incidence, clinical features, treatment, and outcomes of immune checkpoint inhibitor (ICI) hepatotoxicity.
E. Miller +6 more
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Hepatotoxicity of the thiazolidinediones
Clinics in Liver Disease, 2003Troglitazone, the first of the thiazolidinediones, caused severe hepatotoxicity including liver failure in several patients. It appears, however, that the thiazolidinediones as a class are not as hepatotoxic as troglitazone. Comparative data at comparable dates of usage indicate that pioglitazone and rosiglitazone are not significant hepatotoxins. This
Keith G. Tolman, Jane Chandramouli
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Acta Medica Scandinavica, 1986
ABSTRACT.Amiodarone has proved very effective in the treatment of otherwise resistant cardiac tachyarrhythmias. The use of amiodarone has, however, been limited due to its serious side‐effects. A patient with cholestatic hepatitis due to amiodarone treatment is presented below and a review of the hepatotoxicity of amiodarone is given.
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ABSTRACT.Amiodarone has proved very effective in the treatment of otherwise resistant cardiac tachyarrhythmias. The use of amiodarone has, however, been limited due to its serious side‐effects. A patient with cholestatic hepatitis due to amiodarone treatment is presented below and a review of the hepatotoxicity of amiodarone is given.
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Journal of Clinical Psychopharmacology, 1997
Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
Martin Kurz +5 more
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Two hundred thirty-eight patients treated with either haloperidol or clozapine were investigated to shed more light on the incidence and severity of antipsychotic-induced liver enzyme increase. Serum glutamic-pyruvic transaminase (SGPT) increase was most frequently seen in both treatment groups.
Martin Kurz +5 more
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Hepatotoxicity of Mercaptopurine
JAMA, 1964In a study of 49 leukemic patients, jaundice occurred in 16 of 38 who were treated with mercaptopurine (6-mercaptopurine), but only in one of 11 not receiving the drug. In eight patients jaundice cleared up rapidly on cessation of mercaptopurine therapy, and there was a recurrence of jaundice in two who were rechallenged with the drug.
Israel Davidsohn, Morton Einhorn
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Possible Pathways of Hepatotoxicity Caused by Chemical Agents.
Current drug metabolism, 2019BACKGROUND Liver injury induced by drugs has become a basic reason for acute liver disease and therefore posed a potential regulatory and clinical challenge over the past few decades and has received greater attention.
R. Mohi-ud-din +4 more
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Hepatotoxicity of dichloromethane
Forensic Science International, 1988We studied hepatotoxicity of dichloromethane using primary cultures of parenchymal cells (hepatocyte) from adult rat livers. The production of carbon monoxide from dichloromethane increased with time, the increased cell number, and the concentration of dichloromethane.
Kenji Mizutani +2 more
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