Results 301 to 310 of about 201,064 (349)
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Amiodarone Hepatotoxicity

Current Vascular Pharmacology, 2008
Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding whether to initiate or continue treatment with this medication. While mostly associated with long-term oral administration of the drug, toxicity has also been reported early during intravenous administration and months after discontinuation of therapy.
Mohamed, Babatin   +2 more
openaire   +2 more sources

Di(2-ethylhexyl) phthalate induced hepatotoxicity in quail (Coturnix japonica) via modulating the mitochondrial unfolded protein response and NRF2 mediated antioxidant defense.

Science of the Total Environment, 2019
Among ubiquitously found environmental contaminants in the ecosystem, di(2-ethylhexyl) phthalate (DEHP) is an important environmental contaminant used as plasticizer in medical and consumer goods. The bioaccumulation and environmental persistence of DEHP
Qi Zhang   +6 more
semanticscholar   +1 more source

Ganciclovir Hepatotoxicity

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1987
A 33‐year‐old male with acquired immunodeficiency syndrome received ganciclovir for presumed cytomegalovirus retinitis. Although results of baseline liver function tests were abnormal, marked elevations of transaminases and alkaline phosphatase occurred when the drug was first instituted, as well as after rechallenge.
B F, Shea   +3 more
openaire   +2 more sources

Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors.

American Journal of Gastroenterology, 2019
INTRODUCTION We conducted this study to characterize the incidence, clinical features, treatment, and outcomes of immune checkpoint inhibitor (ICI) hepatotoxicity.
E. Miller   +6 more
semanticscholar   +1 more source

HALOTHANE HEPATOTOXICITY

Lancet, The, 1986
P N, Robinson, B M, Bray
exaly   +3 more sources

Mirtazapine-Induced Hepatotoxicity

Journal of Clinical Gastroenterology, 2002
We report two cases of hepatotoxicity induced by mirtazapine. Two women treated for depression with mirtazapine developed severe hepatotoxicity because of the drug. In the first case, mirtazapine was prescribed for 3 years and the patient developed derangement in liver function with prolonged jaundice, which improved after the withdrawal of mirtazapine.
Yuen, MF   +4 more
openaire   +4 more sources

Drug hepatotoxicity

Clinics in Liver Disease, 2002
Drug-induced liver disease is a relatively common, but often unrecognized, cause of liver injury, primarily because the diagnosis is often not entertained clinically. In addition, drugs are great imitators, capable of producing nearly any clinical scenario and histopathologic lesion.
openaire   +2 more sources

Role of intestinal microbiota-mediated genipin dialdehyde intermediate formation in geniposide-induced hepatotoxicity in rats.

Toxicology and Applied Pharmacology, 2019
Geniposide is a natural hepatotoxic iridoid glycoside. Its hydrolysate of intestinal microbiota, genipin, is thought to be responsible for the hepatotoxicity.
Yi Li   +6 more
semanticscholar   +1 more source

METHOTREXATE HEPATOTOXICITY

Rheumatic Disease Clinics of North America, 1997
Hepatoxicity is a major adverse reaction that can occur during methotrexate treatment of the rheumatic diseases. The pathologic lesions are nonspecific and the pathogenesis is poorly understood. Early studies in psoriasis clearly established a relationship between hepatic injury and several risk factors, particularly alcohol use.
openaire   +2 more sources

Hepatotoxicity

2023
The largest organ in the human body is the liver which captures 2 to 3% of the human body weight, located on the right side of the anterior quadrant in the abdomen and below the anterior hemidiaphragm ribcage. It performs various important functions such as digestion of food, protein production, fluid production, detoxification of waste, etc.
Abu Md Ashif Ikbal   +4 more
openaire   +1 more source

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