Results 161 to 170 of about 7,493 (302)

Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models. [PDF]

Toxicol Sci
Livoti LA, Sison-Young R, Reddyhoff D, Fisher CP, Gardner I, Diaz-Nieto R, Goldring CE, Copple IM.   +7 more
europepmc   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models. [PDF]

Toxicol Sci
Jaeschke H, Ramachandran A.
europepmc   +1 more source

Characterisation of Cyanobacterial Strains Originating from the Baltic Sea with Emphasis on Nodularia and its Toxin, Nodularin [PDF]

, 2000
Lehtimäki, Jaana
core  

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Comparison of Adverse Effect Profiles of Nafcillin and Oxacillin in Pediatric Patients. [PDF]

J Pediatr Pharmacol Ther
Warring SR, Biggs JM, Morgan JA, Parbuoni KA.   +3 more
europepmc   +1 more source

Microbubble‐Based Ultrasound Contrast Agents in Contrast‐Enhanced Ultrasonography for Managing Portal Hypertension in Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
As the hepatic venous pressure gradient (HVPG) remains the current gold standard for diagnosing portal hypertension in cirrhosis, its clinical application is limited by invasiveness, high cost, and restricted availability. Given the urgent need for noninvasive techniques to dynamically monitor portal vein pressure (PVP), contrast‐enhanced ...
Danping Huang, Zefeng Liu, Lingling Liu, Fen Huang, Wenjuan Wang, Guo Zhang   +5 more
wiley   +1 more source

Microalgae toxins in food products and impact on human health: a review. [PDF]

Front Nutr
Withana WATN, Gunarathna DMDI, Dissanayake DMGI, Rathnayake AI, de Zoysa HKS, Waisundara VY.   +5 more
europepmc   +1 more source

Fate and effects of Nodularia spumigena and its toxin, nodularin, in Baltic Sea planktonic food webs [PDF]

, 2006
Karjalainen, Miina
core  

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source