Results 251 to 260 of about 7,493 (302)
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Digestive Diseases, 1995
Although essential for life, iron in excessive amounts may be toxic. The liver is particularly subject to the toxic effects of iron, since it is the major site of iron storage. Several inherited and acquired human disorders may result in hepatic iron overload, the most common of which are genetic hemochromatosis (GH) and transfusional iron overload. GH
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Although essential for life, iron in excessive amounts may be toxic. The liver is particularly subject to the toxic effects of iron, since it is the major site of iron storage. Several inherited and acquired human disorders may result in hepatic iron overload, the most common of which are genetic hemochromatosis (GH) and transfusional iron overload. GH
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Papaverine Revisited as a Hepatotoxin
New England Journal of Medicine, 1969The proliferation of therapeutic agents during the past quarter-century has been accompanied by an increased frequency of drug-induced hepatic disease.1 , 2 Usually, the ability of an agent to produce hepatic injury is recognized within a few years of its introduction into clinical use.
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Hepatotoxin-induced hypertyrosinemia and its toxicological significance
Archives of Toxicology, 2006A (1)H Nuclear Magnetic Resonance (NMR) spectroscopic investigation of the effects of single doses of four model hepatotoxins on male Sprague-Dawley rats showed that hypertyrosinemia was induced by three of the treatments (ethionine 300 mg/kg, galactosamine hydrochloride 800 mg/kg and isoniazid 400 mg/kg) but not by the fourth (thioacetamide 200 mg/kg).
T Andrew, Clayton +7 more
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Are Mould Hepatotoxins Responsible for Kava Hepatotoxicity?
Phytotherapy Research, 2012Previous studies with kava components such as kavalactones, pipermethystine and flavokavain B have demonstrated hepatotoxicity from these constituents. Regardless, there has recently been speculation that adulterants or impurities such as the mould hepatotoxin aflatoxin are a more likely cause of kava hepatotoxicity, despite a paucity of supporting ...
Anthony, Rowe, Iqbal, Ramzan
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Nitrostigmin, ein direkt wirkendes Hepatotoxin?
1974Bei der Verlaufskontrolle von Vergiftungen mit Nitrostigmin, einem Cholinesterasehemmer, der in Deutschland unter dem Handelsnamen E 605® als Pflanzenschutzmittel viel verwendet wird, sind wiederholt Zeichen einer Leberschadigung beobachtet worden. Diese Zeichen, wie z. B.
S. Okonek, G. Boelcke
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Hepatotoxin-induced hypertaurinuria: a proton NMR study
Archives of Toxicology, 1990The urinary excretion of taurine by rats after dosing with various hepatotoxins has been investigated by 1H NMR spectroscopy. After single hepatotoxic doses of hydrazine, carbon tetrachloride, 1-naphthylisothiocyanate, or thioacetamide there was biochemical and histopathological evidence of hepatic damage. Proton NMR spectroscopy of the urine collected
S M, Sanins +3 more
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Investigations into a Hepatotoxin in Lupin Roughage
Research in Veterinary Science, 1970Preliminary investigations into the chemical nature of a hepatotoxic factor which sometimes occurs in dried lupin roughage, particularly in Western Australia, have been carried out. Results indicated it was not an alkaloid. Its properties suggested the presence of phenolic and/or acidic groups.
D S, Petterson, W H, Parr
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Identification of hepatotoxin‐producing cyanobacteria by DNA‐chip
Environmental Microbiology, 2008Summary We developed a new tool to detect and identify hepatotoxin‐producing cyanobacteria of the genera Anabaena , Microcystis , Planktothrix , Nostoc and
Anne Rantala +4 more
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Removal of a potent cyanobacterial hepatotoxin by peat
Journal of Environmental Science and Health, Part A, 2010Microcystins (cyclic heptapeptides), produced by a number of freshwater cyanobacteria, are of health concern in potable water supplies. In this article, the adsorptive removal of microcystin-RR (MCRR) from the aqueous solution by a low-cost adsorbent, peat, was investigated. The BET surface area of peat was found to be 12.134 m2/g.
Sathishkumar, O. +4 more
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