Results 21 to 30 of about 8,076 (162)

Seasonal dynamics of the wild rodent faecal virome

Molecular Ecology, Volume 32, Issue 17, Page 4763-4776, September 2023., 2023
Abstract Viral discovery studies in wild animals often rely on cross‐sectional surveys at a single time point. As a result, our understanding of the temporal stability of wild animal viromes remains poorly resolved. While studies of single host–virus systems indicate that host and environmental factors influence seasonal virus transmission dynamics ...
Jayna Raghwani, Christina L. Faust, Sarah François, Dung Nguyen, Kirsty Marsh, Aura Raulo, Sarah C. Hill, Kris V. Parag, Peter Simmonds, Sarah C. L. Knowles, Oliver G. Pybus   +10 more
wiley   +1 more source

Phosphorylation of enteroviral 2Apro at Ser/Thr125 benefits its proteolytic activity and viral pathogenesis

Journal of Medical Virology, Volume 95, Issue 1, January 2023., 2023
Abstract Enteroviral 2A proteinase (2Apro), a well‐established and important viral functional protein, plays a key role in shutting down cellular cap‐dependent translation, mainly via its proteolytic activity, and creating optimal conditions for Enterovirus survival.
Yuya Wang, Wenjia Zou, Yan Niu, Sanyuan Wang, Bangtao Chen, Rui Xiong, Peng Zhang, Zhijun Luo, Yong Wu, Changfa Fan, Zhaohua Zhong, Ping Xu, Yihong Peng   +12 more
wiley   +1 more source

Hepatitis A: Viral Structure, Classification, Life Cycle, Clinical Symptoms, Diagnosis Error, and Vaccination

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2023, Issue 1, 2023., 2023
Hepatitis A virus (HAV) is one of the well‐known viruses that cause hepatitis all around the globe. Although this illness has decreased in developed countries due to extensive immunization, numerous developing and under‐developed countries are struggling with this virus.
Omid Gholizadeh, Sama Akbarzadeh, Mohamad Ghazanfari Hashemi, Marjan Gholami, Parya Amini, Zahra Yekanipour, Raheleh Tabatabaie, Saman Yasamineh, Parastoo Hosseini, Vahdat Poortahmasebi, Lalit Batra   +10 more
wiley   +1 more source

Viral hepatitis in pregnancy

Journal of Viral Hepatitis, Volume 29, Issue 10, Page 844-861, October 2022., 2022
Abstract Viral hepatitis is caused by a heterogenous group of viral agents representing a wide range of phylogenetic groups. Many viruses can involve the liver and cause liver injury but only a subset are delineated as ‘hepatitis viruses’ based upon their primary site of replication and tropism for hepatocytes which make up the bulk of the liver cell ...
Mohamed Tarek M. Shata, Helal F. Hetta, Yeshika Sharma, Kenneth E. Sherman   +3 more
wiley   +1 more source

Picornavirus translation strategies

FEBS Open Bio, Volume 12, Issue 6, Page 1125-1141, June 2022., 2022
Upon the entry of the viral RNA into susceptible cells, cis‐ and trans‐regulatory elements coordinately determine picornavirus protein synthesis. Early in the infection, the cap‐dependent translation of host mRNAs is shut down, while viral RNA takes advantage of the IRES element, resulting in efficient synthesis of viral proteins.
Rosario Francisco‐Velilla, Azman Embarc‐Buh, Salvador Abellan, Encarnacion Martinez‐Salas   +3 more
wiley   +1 more source

Epidemiological Study of Hepatitis A Infection in Eastern Bulgaria

Folia Medica, 2017
Background: Hepatitis A virus (HAV) infection is an acute, self-limited liver disease transmitted usually through the faecal-oral route via person-to-person contact.
Tsankova Gabriela St., Todorova Tatina T., Ermenlieva Neli M., Popova Tsvetelina K., Tsankova Dayana T.   +4 more
doaj   +1 more source

The Acute Liver Injury in Mice Caused by Nano-Anatase TiO [PDF]

, 2009
Although it is known that nano-TiO2or other nanoparticles can induce liver toxicities, the mechanisms and the molecular pathogenesis are still unclear.
Linglan Ma, Jinfang Zhao, Jue Wang, Jie Liu, Yanmei Duan, Huiting Liu, Na Li, Jingying Yan, Jie Ruan, Han Wang, Fashui Hong, JS Brown, WG Kreyling, G Oberdoerster, G Oberdörster, J Muller, HW Chen, TT Win-Shwe, JX Wang, CM Sayes, F Afaq, G Oberdörster, HT Liu, S Ghosh, RR Zhu, P Yang, KJ Livak, LD Ke, WH Liu, D Hohr, JX Wang, JX Wang   +31 more
core   +1 more source

Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen‐positive pregnant women

Food Science &Nutrition, Volume 10, Issue 1, Page 3-11, January 2022., 2022
Abstract To investigate whether HBV genotype influences the effect of tenofovir and telbivudine on HBV DNA and RNA levels in HBsAg‐positive pregnant women. This was a retrospective study of 74 HBsAg‐positive pregnant women in Guizhou of China. All patients were treated with telbivudine or tenofovir from 12 weeks of pregnancy and HBV infection to the ...
Baofang Zhang, Lei Yu, Mingliang Cheng, Quan Zhang, Jun Wu, Jing Yang, Qin Liu, Shuang Lu, Xueke Zhao, KaiSheng Deng, Yongmei Liu, Jun Wang, Peiling Zhao   +12 more
wiley   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar, Altschul, Arturo Talavera, Beales, Beckmann, Bosch, Burritt, Burritt, Clark, Cohen, Collins, Cuthbert, David I. Stott, de la Cruz, Delmastro, Ela M. Perez, Emini, Enshell-Seijffers, Felici, Folgori, Folgori, Frank Camacho, Gomara, Hollinger, Hoogenboon, Irving, Lemon, Lemon, Lemon, Lemon, Lemon, Lemon, Marston, Martin, Mattioli, Nainan, Neduva, Nevis Amin, Osmany G. Larralde, Partidos, Perea, Perez, Ping, Ping, Prezzi, Raiza Martinez, Reed, Sambrook, Scholfield, Stapleton, Stapleton, Stapleton, Verdaguer, Wan, Zhang   +54 more
core   +1 more source

Metagenomic analysis of viromes in tissues of wild Qinghai vole from the eastern Tibetan Plateau

Scientific Reports, 2022
Rodents are natural reservoirs of diverse zoonotic viruses and widely distributed on the Tibetan Plateau. A comprehensive understanding of the virome in local rodent species could provide baseline of viral content and assist in efforts to reduce the risk
Xiaozhou He, Xu Wang, Guohao Fan, Fan Li, Weiping Wu, Zhenghuan Wang, Meihua Fu, Xu Wei, Shuo Ma, Xuejun Ma   +9 more
doaj   +1 more source