Picornavirus translation strategies [PDF]
The genome of viruses classified as picornaviruses consists of a single monocistronic positive strand RNA. The coding capacity of these RNA viruses is rather limited, and thus, they rely on the cellular machinery for their viral replication cycle.
Rosario Francisco‐Velilla +3 more
doaj +5 more sources
Picornavirus Subversion of the Autophagy Pathway [PDF]
While autophagy has been shown to act as an anti-viral defense, the Picornaviridae avoid and, in many cases, subvert this pathway to promote their own replication.
William T. Jackson, Kathryn A. Klein
doaj +4 more sources
New Parvoviruses and Picornavirus in Tissues and Feces of Foals with Interstitial Pneumonia [PDF]
Six foals with interstitial pneumonia of undetermined etiology from Southern California were analyzed by viral metagenomics. Spleen, lung, and colon content samples obtained during necropsy from each animal were pooled, and nucleic acids from virus-like ...
Eda Altan +8 more
doaj +2 more sources
Complete genome sequence of a novel picornavirus, canine picornavirus, discovered in dogs [PDF]
We discovered a novel canine picornavirus in fecal, nasopharyngeal, and urine samples from dogs. The coding potential of its genome (5'-VP4-VP2-VP3-VP1-2A-2B-2C-3A-3B-3C pro-3D pol-3', where 3C pro is 3' protease and 3D pol is 3D polymerase) is similar ...
Woo, PCY +6 more
core +5 more sources
Structural diversity and biological role of the 5’ untranslated regions of picornavirus
The genomic arrangement of most picornavirus of the Picornaviridae family shares a similar monocistronic genomic pattern and a defining organizational feature.
Weijun Cao, Haixue Zheng
exaly +2 more sources
Detection and Characterization of a Novel Picornavirus in European Badger (Meles meles)
The recent development of unbiased metagenomic next-generation sequencing has provided a richer view of the wild animal virome making it necessary to expand the knowledge about virus diversity in wildlife, as well as to monitor their potential ...
Andrea Palombieri +8 more
doaj +2 more sources
Extending the Enterovirus Lead: Could a Related Picornavirus be Responsible for Diabetes in Humans?
We found an association between the abundance of rodents in the wild and onset of type 1 diabetes (T1D) in humans. A picornavirus named Ljungan virus (LV) was subsequently isolated from wild bank voles.
William Klitz, Bo Niklasson
doaj +2 more sources
Multiple functions of the nonstructural protein 3D in picornavirus infection [PDF]
3D polymerase, also known as RNA-dependent RNA polymerase, is encoded by all known picornaviruses, and their structures are highly conserved. In the process of picornavirus replication, 3D polymerase facilitates the assembly of replication complexes and ...
Chenxia Xu +83 more
doaj +2 more sources
Genetic characterization of two novel picornaviruses from birds, white-tailed eagle (Haliaeetus albicilla) and pied avocet (Recurvirostra avosetta) in Hungary [PDF]
In this study, two novel picornaviruses (eagle/WE6/HUN/2014, PV454551-PV454552 and avocet/PA12/HUN/2018, PV454553) were detected in white-tailed eagle (Haliaeetus albicilla) and pied avocet (Recurvirostra avosetta) in Hungary, and characterized by next ...
Benigna Balázs +7 more
doaj +2 more sources
Novel Picornavirus in Lambs with Severe Encephalomyelitis [PDF]
Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom.
Patricia A. Pesavento +27 more
core +5 more sources

