Results 1 to 10 of about 24,514 (173)

Picornavirus Subversion of the Autophagy Pathway [PDF]

Viruses, 2011
While autophagy has been shown to act as an anti-viral defense, the Picornaviridae avoid and, in many cases, subvert this pathway to promote their own replication.
William Jackson
exaly   +5 more sources

Apoptosis and Autophagy in Picornavirus Infection [PDF]

Frontiers in Microbiology, 2019
Cell death is a fundamental process in maintaining cellular homeostasis, which can be either accidental or programed. Programed cell death depends on the specific signaling pathways, resulting in either lytic or non-lytic morphology.
Sai Mao, Anchun Cheng, Di Sun
exaly   +5 more sources

Picornavirus translation strategies

FEBS Open Bio, 2022
The genome of viruses classified as picornaviruses consists of a single monocistronic positive strand RNA. The coding capacity of these RNA viruses is rather limited, and thus, they rely on the cellular machinery for their viral replication cycle.
Rosario Francisco‐Velilla, Azman Embarc‐Buh, Salvador Abellan, Encarnacion Martinez‐Salas   +3 more
doaj   +4 more sources

New Parvoviruses and Picornavirus in Tissues and Feces of Foals with Interstitial Pneumonia

Viruses, 2021
Six foals with interstitial pneumonia of undetermined etiology from Southern California were analyzed by viral metagenomics. Spleen, lung, and colon content samples obtained during necropsy from each animal were pooled, and nucleic acids from virus-like ...
Patricia Pesavento, Eda Altan, Yanpeng Li   +2 more
exaly   +3 more sources

Extracellular Vesicles Released by Picornavirus‐Infected Cells Modify Antiviral Immune Cell Responses [PDF]

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei, Janine T. A. T. Stienstra, Margarida Viola, Renee G. C. Maas, Kyra A. Y. Defourny, Erik Mul, Saskia C. A. de Jager, Joost P. G. Sluijter, Frank J. M. van Kuppeveld, Esther N. M. Nolte‐‘t Hoen   +9 more
wiley   +2 more sources

Asymptomatic Mycoplasma pneumoniae Infections in Children During a Mycoplasma Outbreak [PDF]

Acta Paediatrica, Volume 115, Issue 7, Page 1496-1502, July 2026.
ABSTRACT Aim The aim of this study was to investigate the occurrence of M. pneumoniae detections in asymptomatic children during an outbreak. Methods We prospectively recruited symptomatic and asymptomatic children under 18 years of age between 1 January and 1 November 2024. Picornavirus positivity was also assessed in both groups.
Minna Honkila, Ville Lindholm, Anna‐Karoliina Ojala, Ulla Koskela, Tytti Pokka, Vesa Mäki‐Koivisto, Suvi Mattila, Terhi Ruuska‐Loewald   +7 more
wiley   +2 more sources

Picornavirus inhibitors

Pharmacology & Therapeutics, 1994
Picornaviruses are among the best understood animal viruses in molecular terms. A number of important human and animal pathogens are members of the Picornaviridae family. The genome organization, the different steps of picornavirus growth and numerous compounds that have been reported as inhibitors of picornavirus functions are reviewed.
Luis Carrasco
exaly   +3 more sources

Genetic characterization of two novel picornaviruses from birds, white-tailed eagle (Haliaeetus albicilla) and pied avocet (Recurvirostra avosetta) in Hungary. [PDF]

Sci Rep
In this study, two novel picornaviruses (eagle/WE6/HUN/2014, PV454551-PV454552 and avocet/PA12/HUN/2018, PV454553) were detected in white-tailed eagle (Haliaeetus albicilla) and pied avocet (Recurvirostra avosetta) in Hungary, and characterized by next ...
Balázs B, Boros Á, Pankovics P, Mátics R, Urbán P, Herczeg R, Knowles NJ, Reuter G.   +7 more
europepmc   +2 more sources

Multiple functions of the nonstructural protein 3D in picornavirus infection

Frontiers in Immunology
3D polymerase, also known as RNA-dependent RNA polymerase, is encoded by all known picornaviruses, and their structures are highly conserved. In the process of picornavirus replication, 3D polymerase facilitates the assembly of replication complexes and ...
Shaqiu Zhang, Zhang Shaqiu, Ou Xumin
exaly   +3 more sources

CaFÉ: A Sensitive, Low-Cost Filtration Method for Detecting Polioviruses and Other Enteroviruses in Residual Waters

Frontiers in Environmental Science, 2022
Acute flaccid paralysis (AFP) surveillance has been used to identify polio cases and target vaccination campaigns since the inception of the Global Poliovirus Eradication Initiative (GPEI) in 1988.
Hanen Belgasmi, Stacey Jeffries Miles, Leanna Sayyad, Kimberly Wong, Chelsea Harrington, Nancy Gerloff, Angela D Coulliette-Salmond, Angela D Coulliette-Salmond, Ratigorn Guntapong, Ratana Tacharoenmuang, Apiradee Isarangkul Na Ayutthaya, Lea Necitas G. Apostol, Ma.Anne-Lesley D. Valencia, Cara C. Burns, Gloria-Rey Benito, Everardo Vega   +15 more
doaj   +1 more source