Results 1 to 10 of about 78,348 (310)

Pathogenicity and virulence of hepatitis A virus

open access: yesVirulence, 2021
Hepatitis A is an acute infection of the liver, which is mostly asymptomatic in children and increases the severity with age. Although in most patients the infection resolves completely, in a few of them it may follow a prolonged or relapsed course or ...
Rosa M Pintó   +6 more
doaj   +1 more source

Employing Nanosafety Standards in a Nanomaterial Research Environment: Lessons Learned and Refinement Potential

open access: yesStandards, 2022
Extensive research is currently being conducted on nanotechnologies worldwide, and the applications of nanomaterials are continuously expanding.
Ioannis Kokkinopoulos   +4 more
doaj   +1 more source

Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

open access: yesViruses, 2022
Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region.
Jenniffer Angulo   +7 more
doaj   +1 more source

Utilisation of forecasting technology for improving construction logistics in Nigeria

open access: yesActa Structilia, 2020
The need to investigate new technology for forecasting purposes in construction logistics is due to the fact that the forecasting ability (modern technology utilisation) of the Nigerian construction sector, in terms of logistics management, is relatively
Yahaya Isah   +2 more
doaj   +1 more source

Structural diversity and biological role of the 5’ untranslated regions of picornavirus

open access: yesRNA Biology, 2023
The genomic arrangement of most picornavirus of the Picornaviridae family shares a similar monocistronic genomic pattern and a defining organizational feature.
Tingyu Peng   +5 more
doaj   +1 more source

Collecting Distributed Knowledge For Community’s Smart Changes

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2013
The paper deals with the role of ICT in innovating government’s and the whole process of “policy production process”. By enhancing the connections between various governmental and social organizations, ICT supported knowledge flow s and the associated ...
Alessandro Sciullo, Sylvie Occelli
doaj   +1 more source

Searching for IRES [PDF]

open access: yesRNA, 2006
The cell has many ways to regulate the production of proteins. One mechanism is through the changes to the machinery of translation initiation. These alterations favor the translation of one subset of mRNAs over another. It was first shown that internal ribosome entry sites (IRESes) within viral RNA genomes allowed the production of viral proteins more
Stephen D, Baird   +3 more
openaire   +2 more sources

Production and Application of Multicistronic Constructs for Various Human Disease Therapies

open access: yesPharmaceutics, 2019
The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes.
Alisa A. Shaimardanova   +7 more
doaj   +1 more source

Network Screening for Smarter Road Sites: A Regional Case

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2014
Road safety has been a main societal and policy issue in many European countries since the early years of last decade. After the 2000-2010 Road Safety Programme launched by the European Commission, in 2011 the Commission adopted the new 2020 programme ...
Attila Grieco   +3 more
doaj   +1 more source

Promotion of Viral IRES-Mediated Translation Initiation under Mild Hypothermia. [PDF]

open access: yesPLoS ONE, 2015
Internal ribosome entry site (IRES)-mediated translation is an essential replication step for certain viruses. As IRES-mediated translation is regulated differently from cap-dependent translation under various cellular conditions, we sought to ...
Maria Licursi   +3 more
doaj   +1 more source

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