Results 11 to 20 of about 169,975 (290)
A bicistronic viral genome uses a compact type IV IRES near its 3′ end to express a transmembrane protein [PDF]
Cell ReportsSummary: Hepatitis C virus (HCV) and many other RNA viruses contain a type IV internal ribosome entry site (IRES) in their 5′ untranslated region (UTR). These IRES RNAs interact directly with the ribosome, enabling cap-independent translation initiation.
Madeline E. Sherlock +2 more
doaj +2 more sources
Enhancing Circular RNA Translation Efficiency Through Dual Internal Ribosome Entry Sites [PDF]
BiologyCircular RNA (circRNA) has emerged as a promising vector for drug delivery because, unlike linear mRNA, it does not require costly chemical modifications and offers greater stability and sustained expression in cells.
Yawen Sun +6 more
doaj +2 more sources
Comparison of the Regulatory Effects of Host Factors on Viral Internal Ribosomal Entry Sites [PDF]
Veterinary SciencesHost factors play critical roles in viral IRES-mediated translation by modulating the efficiency and specificity of viral protein synthesis. In this study, we used small interfering RNA (siRNA) treatment to silence and plasmid-based expression to ...
Rupaly Akhter +4 more
doaj +2 more sources
Life cycle assessment of advanced building materials towards NZEBs [PDF]
E3S Web of Conferences, 2022 Buildings are responsible for 40% of energy consumption annually in Europe, along with the respective greenhouse gas emissions. To mitigate these impacts, intensive research is ongoing in the sector of the Nearly Zero-Energy Buildings (NZEBs).
Antypa Despoina +9 more
doaj +1 more source
Frontiers in Bioscience-Elite, 2022 Background: Eukaryotic initiation factor (eIF) 4G plays an important role in assembling the initiation complex required for ribosome binding to mRNA and promote translation.
Mateen A. Khan
doaj +1 more source
Frontiers in Environmental Science, 2021 Tanzania is one of the East African countries most vulnerable to climate change impacts. Droughts and floods in 2015–16 had devastating effects on food production, crop failures and livestock deaths reaching record levels.
Idil Ires, Idil Ires
doaj +1 more source
Near-IR & Mid-IR Silicon Photonics Modulators
Sensors, 2022 As the silicon photonics field matures and a data-hungry future looms ahead, new technologies are required to keep up pace with the increase in capacity demand. In this paper, we review current developments in the near-IR and mid-IR group IV photonic modulators that show promising performance.
Georgi V. Georgiev +7 more
openaire +4 more sources
On the Relation Between Active Network Length and Catchment Discharge
Geophysical Research Letters, 2022 The ever‐changing hydroclimatic conditions of the landscape induce ceaseless variations in the wet channel length (L) and the streamflow (Q) of a catchment.
Nicola Durighetto, Gianluca Botter
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A novel Bcr-Abl–mTOR–eIF4A axis regulates IRES-mediated translation of LEF-1 [PDF]
Open Biology, 2014 Internal ribosome entry sites (IRESs) in cellular mRNAs direct expression of growth-promoting factors through an alternative translation mechanism that has yet to be fully defined.
Becky Pinjou Tsai +10 more
doaj +1 more source
Standards, 2022 Extensive research is currently being conducted on nanotechnologies worldwide, and the applications of nanomaterials are continuously expanding.
Ioannis Kokkinopoulos +4 more
doaj +1 more source