Results 21 to 30 of about 169,975 (290)

Pathogenicity and virulence of hepatitis A virus

Virulence, 2021
Hepatitis A is an acute infection of the liver, which is mostly asymptomatic in children and increases the severity with age. Although in most patients the infection resolves completely, in a few of them it may follow a prolonged or relapsed course or ...
Rosa M Pintó, Francisco-Javier Pérez-Rodríguez, Maria-Isabel Costafreda, Gemma Chavarria-Miró, Susana Guix, Enric Ribes, Albert Bosch   +6 more
doaj   +1 more source

Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

Viruses, 2022
Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region.
Jenniffer Angulo, C. Joaquín Cáceres, Nataly Contreras, Leandro Fernández-García, Nathalie Chamond, Melissa Ameur, Bruno Sargueil, Marcelo López-Lastra   +7 more
doaj   +1 more source

Utilisation of forecasting technology for improving construction logistics in Nigeria

Acta Structilia, 2020
The need to investigate new technology for forecasting purposes in construction logistics is due to the fact that the forecasting ability (modern technology utilisation) of the Nigerian construction sector, in terms of logistics management, is relatively
Yahaya Isah, Winston Shakantu, Saidu Ibrahim   +2 more
doaj   +1 more source

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. [PDF]

, 2013
The internal ribosome entry site (IRES) of the hepatitis C virus (HCV) drives noncanonical initiation of protein synthesis necessary for viral replication.
A Ben-Shem, A Devaraj, AA Malygin, AD Petropoulos, AY Keel, Breanna S Vollmar, C Chen, CM Spahn, CS Fraser, CS Fraser, D Boehringer, D Hartz, D Sousa, Dan Shi, DD Ian'shina, DV Sizova, EF Pettersen, F Odreman-Macchioli, F Peske, F Robert, GA Otto, GJ Kleywegt, H Ji, IB Lomakin, IM Terenin, J Bukh, J Rabl, J Wower, JA Mindell, JE Wilson, Jeffrey S Kieft, JH Kim, JM Fringer, JR Lytle, JR Lytle, JS Kieft, JS Kieft, K Tsukiyama-Kohara, KE Berry, KI Kalliampakou, LA Passmore, M Honda, M Ohi, M Selmer, M Stoneley, M van Heel, ME Filbin, Megan E Filbin, MG Acker, MM Yusupov, N Grigorieff, N Locker, O Galkin, P Antúnez de Mayolo, P Simmonds, PJ Lukavsky, PJ Lukavsky, RE Monro, RJ Jackson, S Fukushi, S Uemura, SM Dibrov, T Döring, Tamir Gonen, TV Pestova, TV Pestova, U Geigenmüller, VG Kolupaeva, Y Yu   +68 more
core   +1 more source

Collecting Distributed Knowledge For Community’s Smart Changes

TeMA: Journal of Land Use, Mobility and Environment, 2013
The paper deals with the role of ICT in innovating government’s and the whole process of “policy production process”. By enhancing the connections between various governmental and social organizations, ICT supported knowledge flow s and the associated ...
Alessandro Sciullo, Sylvie Occelli
doaj   +1 more source

Structural diversity and biological role of the 5’ untranslated regions of picornavirus

RNA Biology, 2023
The genomic arrangement of most picornavirus of the Picornaviridae family shares a similar monocistronic genomic pattern and a defining organizational feature.
Tingyu Peng, Fayu Yang, Fan Yang, Weijun Cao, Haixue Zheng, Zixiang Zhu   +5 more
doaj   +1 more source

Relevance of intermittent rivers and streams in agricultural landscape and their impact on provided ecosystem services—a Mediterranean case study [PDF]

, 2019
Ecosystem services (ES), as an interconnection of the landscape mosaic pieces, along with temporal rivers (IRES) are an object of research for environmental planners and ecological economists, among other specialists.
Amélie Truchy, Ana Loures, Belsky, Caldas, Collares-Pereira, Elena Aydin, Estrela, Goosens, Gordon, Haines-Young, Hasan, Haygarth, José Telo da Gama, Jurík, Koundouri, Kubinský, Luis Loures, Nunes, Pires, Pyrce, Rui Alexandre Castanho, Tatiana Kaletová, Van Kerckhoven, Wood, Špulerová, Šurda   +25 more
core   +1 more source

Production and Application of Multicistronic Constructs for Various Human Disease Therapies

Pharmaceutics, 2019
The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes.
Alisa A. Shaimardanova, Kristina V. Kitaeva, Ilmira I. Abdrakhmanova, Vladislav M. Chernov, Catrin S. Rutland, Albert A. Rizvanov, Daria S. Chulpanova, Valeriya V. Solovyeva   +7 more
doaj   +1 more source

Network Screening for Smarter Road Sites: A Regional Case

TeMA: Journal of Land Use, Mobility and Environment, 2014
Road safety has been a main societal and policy issue in many European countries since the early years of last decade. After the 2000-2010 Road Safety Programme launched by the European Commission, in 2011 the Commission adopted the new 2020 programme ...
Attila Grieco, Chiara Montaldo, Sylvie Occelli, Silvia Tarditi   +3 more
doaj   +1 more source

Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions [PDF]

, 2013
Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) is modified to form diphthamide. A role for eEF2 in cellular stress responses is highlighted by the fact that eEF2 is sensitive to
Argüelles Castilla, Sandro, Ayala Gómez, Antonio, Camandola, Simonetta, Cutler, Roy G.   +3 more
core   +1 more source