Promotion of Viral IRES-Mediated Translation Initiation under Mild Hypothermia. [PDF]
PLoS ONE, 2015 Internal ribosome entry site (IRES)-mediated translation is an essential replication step for certain viruses. As IRES-mediated translation is regulated differently from cap-dependent translation under various cellular conditions, we sought to ...
Maria Licursi +3 more
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The 5 ' untranslated region of protein kinase C delta directs translation by an internal ribosome entry segment that is most active in densely growing cells and during apoptosis. [PDF]
, 2002 Protein kinase Cdelta (PKCdelta) is a member of the PKC family of phospholipid-dependent serine/threonine kinases and is involved in cell proliferation, apoptosis, and differentiation.
Morrish, B.C., Rumsby, M.G.
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Viral IRES prediction system - a web server for prediction of the IRES secondary structure in silico. [PDF]
PLoS ONE, 2013 The internal ribosomal entry site (IRES) functions as cap-independent translation initiation sites in eukaryotic cells. IRES elements have been applied as useful tools for bi-cistronic expression vectors.
Jun-Jie Hong +3 more
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Viruses, 2021 Senecavirus A (SVA) is a picornavirus that causes vesicular disease in swine and the only member of the Senecavirus genus. Like in all members of Picornaviridae, the 5′ untranslated region (5’UTR) of SVA contains an internal ribosome entry site (IRES ...
Nana Wang +9 more
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Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation. [PDF]
, 2013 The initiation of protein synthesis plays an essential regulatory role in human biology. At the center of the initiation pathway, the 13-subunit eukaryotic translation initiation factor 3 (eIF3) controls access of other initiation factors and mRNA to the
Arias-Palomo, Ernesto +6 more
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HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication. [PDF]
PLoS ONE, 2015 EV71 (enterovirus 71) RNA contains an internal ribosomal entry site (IRES) that directs cap-independent initiation of translation. IRES-dependent translation requires the host's translation initiation factors and IRES-associated trans-acting factors ...
Jing-Yi Lin, Gary Brewer, Mei-Ling Li
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IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animals [PDF]
, 2016 BACKGROUND: Foot-and-mouth disease virus (FMDV) possess a positive sense, single stranded RNA genome. Internal ribosomal entry site (IRES) element exists within its 5′ untranslated region (5′UTR) of the viral RNA.
Kyoko Tsukiyama-Kohara +2 more
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Distinct roles for the IIId2 sub-domain in pestivirus and picornavirus internal ribosome entry sites. [PDF]
, 2017 Viral internal ribosomes entry site (IRES) elements coordinate the recruitment of the host translation machinery to direct the initiation of viral protein synthesis. Within hepatitis C virus (HCV)-like IRES elements, the sub-domain IIId(1) is crucial for
Allouche, D +13 more
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Science and Management of Intermittent Rivers and Ephemeral Streams (SMIRES) [PDF]
Research Ideas and Outcomes, 2017 More than half of the global river network is composed of intermittent rivers and ephemeral streams (IRES), which are expanding in response to climate change and increasing water demands. After years of obscurity, the science of IRES has bloomed recently
Thibault Datry +32 more
doaj +2 more sources
Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES–driven RNA localization
Life Science Alliance, 2019 Integration of proteomic data with functional and imaging analysis revealed that Rab1b and ARF5, two ER-Golgi members, are RNA-binding proteins that colocalize with picornavirus IRES-RNA reporters in human cells.
Javier Fernandez-Chamorro +3 more
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