Results 51 to 60 of about 78,348 (310)

Flexible Implantable Silicon Carbide Multi‐Electrode Array (MEA) for Cell Multichannel Recording and Cell Ablation

Advanced Materials Technologies, EarlyView.
Flexible silicon carbide (SiC) microelectrode arrays enable high‐fidelity, multichannel cell extracellular recording and precise localized ablation. SiC has been extensively evaluated to persist long‐term in chronic physiological conditions while remaining robust, with excellent electrical and electrochemical stability.
Minh Anh Huynh, Matthew Barton, Sharda Yadav, Tuan‐Khoa Nguyen, Nam‐Trung Nguyen   +4 more
wiley   +1 more source

La relazione Ires per il 2010 [PDF]

, 2011
- Indice #2- Società, economia e territorio: il quadro generale dell'economia #16- I settori produttivi #55- Le infrastrutture #103- Governo e governance locale #143- La qualità sociale #154- Approfondimenti ...
Ires
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia

eLife, 2022
Internal ribosome entry sites (IRESs) drive translation initiation during stress. In response to hypoxia, (lymph)angiogenic factors responsible for tissue revascularization in ischemic diseases are induced by the IRES-dependent mechanism.
Anne-Claire Godet, Emilie Roussel, Florian David, Fransky Hantelys, Florent Morfoisse, Joffrey Alves, Françoise Pujol, Isabelle Ader, Edouard Bertrand, Odile Burlet-Schiltz, Carine Froment, Anthony K Henras, Patrice Vitali, Eric Lacazette, Florence Tatin, Barbara Garmy-Susini, Anne-Catherine Prats   +16 more
doaj   +1 more source

Relazione annuale 2018. Così lontano, così vicino [PDF]

, 2018
Relazione annuale 2018 ...
Ires Piemonte
core  

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

A La autoantigen homologue is required for the internal ribosome entry site mediated translation of giardiavirus. [PDF]

PLoS ONE, 2011
Translation of Giardiavirus (GLV) mRNA is initiated at an internal ribosome entry site (IRES) in the viral transcript. The IRES localizes to a downstream portion of 5' untranslated region (UTR) and a part of the early downstream coding region of the ...
Srinivas Garlapati, Ashesh A Saraiya, Ching C Wang   +2 more
doaj   +1 more source

Determining the fate of cells transduced with pSSFV-IRES-GFP lentiviral particles injected into the corpus callosum.

, 2018
(A-E) Immunofluorescence staining against astrocytes marker Gfap, Oligodendrocyte lineage cell markers PdgfRα, NG2, Olig2 and neuron marker (NeuN) at 3 weeks post injection (wpi) of pSSFV-IRES-GFP lentiviral particles into the corpora callosa of ...
Akram Mokhtarzadeh Khanghahi (5746418), Mohammad Javan (195590), Wenbin Deng (5746421), Leila Satarian (195586), Hossein Baharvand (157456)   +4 more
core   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source