Results 61 to 70 of about 78,348 (310)
Knowledge and Management of Aquatic EcosystemsRiver flow intermittence is a natural phenomenon intensified by human activities, such as water abstraction and the effects of climate change. A growing number of rivers are predicted to experience intermittent flows, which may impact the diversity and ...
Schiavon Alfredo +7 more
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Considerazioni sul piano per le costruzioni ospedaliere proposto per il Piemonte [PDF]
, 1968 - Indice #5- Direttive ed istruzioni del Ministero dei Lavori Pubblici per la predisposizione di un piano regionale per le costruzioni ospedaliere #11- Le proposte del Provveditorato Regionale alle Opere Pubbliche del Piemonte per la formulazione di un ...
I.R.E.S. Istituto Ricerche Econoico-Sociali +1 more
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Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Avian cell-free translation system based on the cell extract of Gallus gallus embryos
Учёные записки Казанского университета: Серия Естественные наукиCell-free translation systems are gaining increasingly widespread use, from both practical and fundamental standpoints. Their applications are diverse but typically revolve around preparative biosynthesis of proteins in cases where expression in living ...
A. G. Bikmullin +3 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Revista Latinoamericana de Metodología de las Ciencias Sociales, 2020 El objetivo del artículo es iluminar los aportes de la comparación de casos fuertemente contrastados a partir de una investigación sobre las prácticas asociativas en barrios populares de la periferia urbana de París y Buenos Aires.
Arnaud Trenta
doaj +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
Advanced Science, EarlyView.This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Is There a 'Chinese School' of IR? [PDF]
SSRN Electronic Journal, 2012 Research on Chinese International Relations (IR) theory has produced a variety of discourses, including post‐positivist analyses, contributions by area specialists and China watchers, and articles by Chinese IR scholars. These strands, however, hardly overlap or communicate with each other.
openaire +3 more sources
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
Advanced Science, EarlyView.In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
VirusesDengue virus (DENV) is an enveloped, positive sense, single-stranded RNA virus belonging to the Flaviviridae. Translation initiation of the DENV mRNA (vRNA) can occur following a cap-dependent, 5′-3’end-dependent internal ribosome entry site (IRES ...
Leandro Fernández-García +2 more
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