Results 11 to 20 of about 24,514 (173)
Picornavirus Morphogenesis [PDF]
Microbiology and Molecular Biology Reviews, 2014 SUMMARY The Picornaviridae represent a large family of small plus-strand RNA viruses that cause a bewildering array of important human and animal diseases. Morphogenesis is the least-understood step in the life cycle of these viruses, and this process is difficult to study because encapsidation is tightly ...
Ping, Jiang +4 more
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Structural diversity and biological role of the 5’ untranslated regions of picornavirus
RNA Biology, 2023 The genomic arrangement of most picornavirus of the Picornaviridae family shares a similar monocistronic genomic pattern and a defining organizational feature.
Tingyu Peng +5 more
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Molecular Pathology, 2002 Recently, much has been learned about the molecular mechanisms involved in the pathogenesis of picornaviruses. This has been accelerated by the solving of the crystal structures of many members of this virus family. However, one stage of the virus life cycle remains poorly understood: uncoating. How do these simple but efficient pathogens protect their
Smyth, M.S., Martin, Jan H.
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Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Transboundary and Emerging Diseases, Accepted Article., 2022 Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann +3 more
wiley +1 more source
Detection and Characterization of a Novel Picornavirus in European Badger (Meles meles)
Veterinary Sciences, 2022 The recent development of unbiased metagenomic next-generation sequencing has provided a richer view of the wild animal virome making it necessary to expand the knowledge about virus diversity in wildlife, as well as to monitor their potential ...
Andrea Palombieri +8 more
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Extending the Enterovirus Lead: Could a Related Picornavirus be Responsible for Diabetes in Humans?
Microorganisms, 2020 We found an association between the abundance of rodents in the wild and onset of type 1 diabetes (T1D) in humans. A picornavirus named Ljungan virus (LV) was subsequently isolated from wild bank voles.
William Klitz, Bo Niklasson
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Frontiers in Veterinary Science, 2020 The seal picornavirus 1, species Aquamavirus A, is currently the only recognized member of the genus Aquamavirus within the family Picornaviridae. The bear picornavirus 1 was recently proposed as the second species in the genus under the name aquamavirus
Thais C. S. Rodrigues +7 more
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Molecular Therapy: Oncolytics, 2023 Mengovirus is an oncolytic picornavirus whose broad host range allows for testing in immunocompetent cancer models. Two pathogenicity-ablating approaches, polycytidine (polyC) tract truncation and microRNA (miRNA) targets insertion, eliminated the risk ...
Velia Penza +4 more
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PoSE: visualization of patterns of sequence evolution using PAML and MATLAB
BMC Bioinformatics, 2018 Background Determining patterns of nucleotide and amino acid substitution is the first step during sequence evolution analysis. However, it is not easy to visualize the different phylogenetic signatures imprinted in aligned nucleotide and amino acid ...
Kun Zhao +5 more
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Complete Genome Sequence of a Novel Picornavirus, Canine Picornavirus, Discovered in Dogs [PDF]
Journal of Virology, 2012 ABSTRACT We discovered a novel canine picornavirus in fecal, nasopharyngeal, and urine samples from dogs. The coding potential of its genome (5′-VP4-VP2-VP3-VP1-2A-2B-2C-3A-3B-3C pro -3D pol -3′, where 3C pro is 3C protease and 3D pol ...
Lau, SKP +6 more
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