Results 21 to 30 of about 26,015 (214)
PoSE: visualization of patterns of sequence evolution using PAML and MATLAB
BMC Bioinformatics, 2018 Background Determining patterns of nucleotide and amino acid substitution is the first step during sequence evolution analysis. However, it is not easy to visualize the different phylogenetic signatures imprinted in aligned nucleotide and amino acid ...
Kun Zhao +5 more
doaj +1 more source
An epidemic of picornavirus and adenovirus conjunctivitis [PDF]
, 1975 A pandemic of acute haemorrhagic conjunctivitis occurred in south-east Asia during 1970 and 1971, and became epidemic in Lucknow in May 1971. From the conjunctival swabs adenovirus-like agents were isolated in monkey kidney tissue culture; one was typed ...
Mathur, A. +5 more
core +1 more source
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
, 2014 Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, N J +5 more
core +1 more source
Viruses, 2021 Hospital-based and community-based ‘high-risk cohort’ studies investigating humans at risk of zoonotic infection due to occupational or residential exposure to animals were conducted in Vietnam, with diverse viruses identified from faecal samples ...
Lu Lu +6 more
doaj +1 more source
Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis
Advances in Virology, 2010 The RNA-dependent RNA-polymerase, 3Dpol, is an essential component in the picornavirus genome for the replication of single stranded RNA. However, transgenic expression of 3Dpol in mice has antiviral effects.
Jason Kerkvliet +2 more
doaj +1 more source
Rhinovirus Inhibitors: Including a New Target, the Viral RNA
Viruses, 2021 Rhinoviruses (RVs) are the main cause of recurrent infections with rather mild symptoms characteristic of the common cold. Nevertheless, RVs give rise to enormous numbers of absences from work and school and may become life-threatening in particular ...
Antonio Real-Hohn, Dieter Blaas
doaj +1 more source
Metabolites, 2023 The total alcohol extract obtained from the aerial parts of R. stricta and fractions of the liquid–liquid fractionation process were tested against picornavirus-causing foot-and-mouth disease (FMD) based on the traditional use of the plant in Saudi ...
Maged S. Abdel-Kader +7 more
doaj +1 more source
Autoimmunity in picornavirus infections
Current Opinion in Virology, 2016 Enteroviruses are small, non-enveloped, positive-sense single-strand RNA viruses, and are ubiquitously found throughout the world. These viruses usually cause asymptomatic or mild febrile illnesses, but have a propensity to induce severe diseases including type 1 diabetes and pancreatitis, paralysis and neuroinflammatory disease, myocarditis, or ...
Massilamany, Chandirasegara +4 more
openaire +3 more sources
An unexpected, pH-sensitive step of the enterovirus D68 lifecycle
mBio, 2023 Enterovirus D68 (EV-D68) contributes significantly to pathogen-induced respiratory illnesses and severe neurological disorders like acute flaccid myelitis.
David Aponte-Diaz +2 more
doaj +1 more source
Viruses, 2021 Most picornaviruses of the family Picornaviridae are relatively well known, but there are certain “neglected” genera like Bopivirus, containing a single uncharacterised sequence (bopivirus A1, KM589358) with very limited background information.
Zoltán László +6 more
doaj +1 more source