Results 41 to 50 of about 26,015 (214)

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

open access: yesAnimal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng   +7 more
wiley   +1 more source

Tracking poliovirus through wastewater: environmental surveillance insights from Haïti (2020–2023)

open access: yesApplied and Environmental Microbiology
Environmental surveillance (ES) for poliovirus is a critical component of global eradication efforts, enabling the detection of virus circulation in communities, even in the absence of acute flaccid paralysis (AFP) cases.
Hanen Belgasmi-Allen   +11 more
doaj   +1 more source

Enterovirus Transmission by Secretory Autophagy

open access: yesViruses, 2018
Present in many cell types, non-degradative secretory autophagy is a newly discovered pathway in which autophagosomes fuse with the plasma membrane instead of lysosomes.
Yael Mutsafi, Nihal Altan-Bonnet
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Coxsackievirus A6 and Hand, Foot, and Mouth Disease, Finland

open access: yesEmerging Infectious Diseases, 2009
During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland. We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent. CVA6 infections
Riikka Österback   +5 more
doaj   +1 more source

The Picornavirus Precursor 3CD Has Different Conformational Dynamics Compared to 3Cpro and 3Dpol in Functionally Relevant Regions

open access: yesViruses, 2021
Viruses have evolved numerous strategies to maximize the use of their limited genetic material, including proteolytic cleavage of polyproteins to yield products with different functions.
Dennis S. Winston, David D. Boehr
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

Recombinant Viruses from the Picornaviridae Family Occurring in Racing Pigeons

open access: yesViruses
Viruses from Picornaviridae family are known pathogens of poultry, although the information on their occurrence and pathogenicity in pigeons is scarce. In this research, efforts are made to broaden the knowledge on Megrivirus B and Pigeon picornavirus B ...
Ewa Łukaszuk   +2 more
doaj   +1 more source

Fathead minnow picornavirus infected cell culture.

open access: yes, 2014
A) Healthy epithelioma papulosum cyprini cells (EPC), B) EPC cells incubated at 22°C, 6 days post-inoculation with fathead minnow picornavirus (FHMPV-09).
Terry Fei Fan Ng (218510)   +12 more
core   +1 more source

Picornavirus Infection Leading to Immunosuppression [PDF]

open access: yesFuture Virology, 2014
Viruses, such as HIV, hepatitis A, poliovirus, coxsackievirus B3 and foot-and-mouth disease virus, use a variety of mechanisms to suppress the human immune system in order to evade clearance by the host. Therefore, investigating how a few changes in the viral genome of a nonlethal virus can lead to an alteration in disease, from survivable to ...
Matthew F, Cusick   +2 more
openaire   +2 more sources

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