Results 41 to 50 of about 24,514 (173)

Coxsackievirus A6 and Hand, Foot, and Mouth Disease, Finland

Emerging Infectious Diseases, 2009
During fall 2008, an outbreak of hand, foot, and mouth disease (HFMD) with onychomadesis (nail shedding) as a common feature occurred in Finland. We identified an unusual enterovirus type, coxsackievirus A6 (CVA6), as the causative agent. CVA6 infections
Riikka Österback, Tytti Vuorinen, Mervi Linna, Petri Susi, Timo Hyypiä, Matti Waris   +5 more
doaj   +1 more source

The Picornavirus Precursor 3CD Has Different Conformational Dynamics Compared to 3C^pro and 3D^pol in Functionally Relevant Regions

Viruses, 2021
Viruses have evolved numerous strategies to maximize the use of their limited genetic material, including proteolytic cleavage of polyproteins to yield products with different functions.
Dennis S. Winston, David D. Boehr
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Recombinant Viruses from the Picornaviridae Family Occurring in Racing Pigeons

Viruses
Viruses from Picornaviridae family are known pathogens of poultry, although the information on their occurrence and pathogenicity in pigeons is scarce. In this research, efforts are made to broaden the knowledge on Megrivirus B and Pigeon picornavirus B ...
Ewa Łukaszuk, Daria Dziewulska, Tomasz Stenzel   +2 more
doaj   +1 more source

Systematic nomenclature of picornavirus proteins [PDF]

Journal of Virology, 1984
An easily learned convention for systematizing the nomenclature of picornavirus proteins is described. The convention is based upon an idealized map, called the L434 diagram, of the picornavirus polyprotein.
R R, Rueckert, E, Wimmer
openaire   +2 more sources

Coxsackievirus B Infections Are Associated With the Risk of Islet Autoimmunity in Children With Strong Genetic Susceptibility to Type 1 Diabetes—Results From the TRIGR Divia Study

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims Especially, the coxsackievirus B group of enteroviruses has been linked to the development of islet autoimmunity and type 1 diabetes in genetically susceptible individuals. Our aim was to study the possible associations of 10 different microbial infections with islet autoimmunity in a large international prospective study.
Maarit Oikarinen, Amirbabak Sioofy‐Khojine, Leena Puustinen, David Cuthbertson, Jussi Lehtonen, Niila V. V. Jouppila, Johnny Ludvigsson, Leena Hakola, Sari Niinistö, Iris Erlund, Mikael Knip, Jeffrey P. Krischer, Suvi M. Virtanen, Heikki Hyöty, on behalf of the TRIGR Investigators   +14 more
wiley   +1 more source

Identification of the pocket factors in a picornavirus

Archives of Virology, 2003
Bovine enterovirus (BEV), along with other enteroviruses and the rhinoviruses, has a hydrophobic pocket within structural protein VP1. In the crystal structures of these viruses there is electron density commensurate with a non-protein molecule within the pocket.
Smyth, M.S., Martin, Jan H., Pettitt, T., Symonds, A.   +3 more
openaire   +4 more sources

Picornavirus Infection Leading to Immunosuppression [PDF]

Future Virology, 2014
Viruses, such as HIV, hepatitis A, poliovirus, coxsackievirus B3 and foot-and-mouth disease virus, use a variety of mechanisms to suppress the human immune system in order to evade clearance by the host. Therefore, investigating how a few changes in the viral genome of a nonlethal virus can lead to an alteration in disease, from survivable to ...
Matthew F, Cusick, Jane E, Libbey, Robert S, Fujinami   +2 more
openaire   +2 more sources

The C117D oxidation mimic reveals the monomeric structure of SARS‐CoV‐2 main protease

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The SARS‐CoV‐2 main protease (Mpro) is essential for viral replication and functions as a homodimer, with dimerization being critical for catalytic activity. Mpro contains an unusually high number of cysteine residues. Among these, C117 and the catalytic nucleophile C145 can form a reversible disulfide bond under oxidative conditions.
Sam Andress, Matthew J. McLeod, Todd Holyoak   +2 more
wiley   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, Volume 4, Issue 3, Page 293-301, August 2026.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source