Results 51 to 60 of about 26,015 (214)

Reduced SH3RF3 May Protect Against Alzheimer's Disease by Lowering Microglial Pro‐Inflammatory Responses via Modulation of JNK and NFkB Signaling

Glia, Volume 74, Issue 7, July 2026.
SNPs in SH3RF3 decrease the age of onset of Alzheimer's disease (AD). Reduced SH3RF3 blunts human microglial JNK and NFkB signaling and downstream inflammatory cytokine production, which may partially explain how SH3RF3 SNPs protect against AD. ABSTRACT Understanding how high‐risk individuals are protected from Alzheimer's disease (AD) may illuminate ...
Ronak Patel, Rong Cheng, Christopher L. Cardona, Ellen Angeles, Gunjandeep Singh, Sabrina Miller, Archana Ashok, Andrew F. Teich, Angel Piriz, Aleyda Maldonado, Ivonne Z. Jiménez‐Velázquez, Richard Mayeux, Joseph H. Lee, Andrew A. Sproul   +13 more
wiley   +1 more source

Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates [PDF]

, 2015
Bacterial airway colonization is known to alter the airway mucosa immune response in neonates whereas the impact of viruses is unknown. The objective was therefore to examine the effect of respiratory viruses on the immune signature in the airways of ...
Brix, S, Bønnelykke, K, Bisgaard, H, Følsgaard, NV, Følsgaard, Nilofar V., Bønnelykke, Klaus, Chawes, Bo L., Birch, Sune, Kebadze, T, Følsgaard, Nilofar V, Wolsk, Helene M., Johnston, Sebastian L., Hansel, Trevor T, Hansel, TT, Pedersen, Susanne Brix, Johnston, Sebastian L, Birch, S, Kebadze, Tatiana, Wolsk, Helene M, Bisgaard, Hans, Brix, Susanne, Chawes, BL, Bisgaard, Hans Flinker, Hansel, Trevor T., Wolsk, HM, Johnston, SL   +25 more
core   +1 more source

Systematic nomenclature of picornavirus proteins [PDF]

Journal of Virology, 1984
An easily learned convention for systematizing the nomenclature of picornavirus proteins is described. The convention is based upon an idealized map, called the L434 diagram, of the picornavirus polyprotein.
R R, Rueckert, E, Wimmer
openaire   +2 more sources

Identification of a Novel Feline Picornavirus from the Domestic Cat

, 2012
While picornaviruses are known to infect different animals, their existence in the domestic cat was unknown. We describe the discovery of a novel feline picornavirus (FePV) from stray cats in Hong Kong.
Ru Bai, Ying Wu, Kwok-Yung Yuen, Kwok-Hung Chan, Garnet K. Y. Choi, Rachel Y. Y. Fan, Cyril C. Y. Yip, Susanna K. P. Lau, Kenneth K. Y. Lai, Patrick C. Y. Woo   +9 more
core   +2 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

A New Picornavirus Isolated from Bank Voles (Clethrionomys glareolus)

, 1999
A previously unknown picornavirus was isolated from bank voles (Clethrionomys glareolus). Electron microscopy images and sequence data of the prototype isolate, named Ljungan virus, showed that it is a picornavirus.
Kinnunen, L, Matskova, L,, Niklasson, B, Matskova, Ludmila, Hörling, J, Kinnunen, Leena, Olof Hedlund, Kjell, Niklasson, Bo, Benemar, Charlotte, Hyypiä, Timo, Hyypiä, T, Hörnfeldt, Birger, Hedlund, KO, Benemar, C, Winberg, Gösta, Hörling, Jan, Winberg, G,, Hörnfeldt, B   +17 more
core   +1 more source

Picornavirus Cellular Remodeling: Doubling Down in Response to Viral-Induced Inflammation [PDF]

, 2020
Purpose of reviewTo highlight recent findings on how picornavirus infections of the airways and cardiac tissues impact cellular inflammation and remodeling events.Recent findingsRecent published work has revealed that although many picornavirus ...
Semler, Bert L, Bouin, Alexis
core   +1 more source

Progress in human picornavirus research : New findings from the AIROPico consortium [PDF]

, 2019
Several research groups in Europe are active on different aspects of human picornavirus research. The AIROPico (Academia-Industry R&D Opportunities for Picornaviruses) consortium combined the disciplines of pathogenesis, diagnostics and therapy ...
Wolthers, Katja C., Landt, Olfert, Jochmans, Dirk, Neyts, Johan, Palm, Kaia, Koskinen, Janne, Butcher, Sarah J., Sanchez, Neus, Susi, Petri   +8 more
core   +3 more sources

Extracellular Vesicles Released by Picornavirus‐Infected Cells Modify Antiviral Immune Cell Responses

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei, Janine T. A. T. Stienstra, Margarida Viola, Renee G. C. Maas, Kyra A. Y. Defourny, Erik Mul, Saskia C. A. de Jager, Joost P. G. Sluijter, Frank J. M. van Kuppeveld, Esther N. M. Nolte‐‘t Hoen   +9 more
wiley   +1 more source

Foot-and-Mouth Disease Virus Serotype SAT 3 in Long-Horned Ankole Calf, Uganda

Emerging Infectious Diseases, 2015
After a 16-year interval, foot-and-mouth disease virus serotype SAT 3 was isolated in 2013 from an apparently healthy long-horned Ankole calf that grazed close to buffalo in Uganda.
Moses Tefula Dhikusooka, Kirsten Tjørnehøj, Chrisostom Ayebazibwe, Alice Namatovu, Simon Ruhweza, Hans Redlef Siegismund, Sabenzia Nabalayo Wekesa, Preben Normann, Graham J. Belsham   +8 more
doaj   +1 more source