Results 51 to 60 of about 24,514 (173)

Foot-and-Mouth Disease Virus Serotype SAT 3 in Long-Horned Ankole Calf, Uganda

Emerging Infectious Diseases, 2015
After a 16-year interval, foot-and-mouth disease virus serotype SAT 3 was isolated in 2013 from an apparently healthy long-horned Ankole calf that grazed close to buffalo in Uganda.
Moses Tefula Dhikusooka, Kirsten Tjørnehøj, Chrisostom Ayebazibwe, Alice Namatovu, Simon Ruhweza, Hans Redlef Siegismund, Sabenzia Nabalayo Wekesa, Preben Normann, Graham J. Belsham   +8 more
doaj   +1 more source

Seizures following picornavirus infection [PDF]

Epilepsia, 2008
Summary Purpose: We demonstrate the establishment and characterization of a novel virus infection‐induced seizure model in C57BL/6 mice. Methods: C57BL/6 mice were infected with Theiler's murine encephalomyelitis virus (TMEV) or mock infected.
Jane E, Libbey, Nikki J, Kirkman, Matthew C P, Smith, Tomoko, Tanaka, Karen S, Wilcox, H Steve, White, Robert S, Fujinami   +6 more
openaire   +2 more sources

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background Rhinoviruses (RV) are the most common pathogens causing respiratory tract infections, and early childhood RV wheezing illnesses are a known risk factor for childhood asthma. The role of acute upper respiratory tract infections (URTI) caused by different RV species in asthma development is not well known.
Ville Forsström, Matti Waris, Ville Peltola, Laura Toivonen   +3 more
wiley   +1 more source

Noncanonical Poly(A) Polymerase TENT4 Drives Expression of Subgenomic Hepatitis A Virus RNAs in Infected Cells

Viruses
Both hepatitis B virus (HBV), an hepadnavirus with a DNA genome, and hepatitis A virus (HAV), a picornavirus, require the TRAMP-like host ZCCHC14-TENT4 complex for efficient replication.
You Li, Ankit Gupta, Brian N. Papas, David Aponte-Diaz, Jayden M. Harris, Ichiro Misumi, Jason K. Whitmire, Craig E. Cameron, Marcos Morgan, Stanley M. Lemon   +9 more
doaj   +1 more source

Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

Microbiology Spectrum, 2022
Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory tract or the ...
Leanne C. Helgers, Michel S. Bhoekhan, Dasja Pajkrt, Katja C. Wolthers, Teunis B. H. Geijtenbeek, Adithya Sridhar   +5 more
doaj   +1 more source

Updates on intratumoral therapies in melanoma

Cancer, Volume 132, Issue 13, 1 July 2026.
Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma, Alyssa K. Steimle, Janmesh D. Patel, Caroline Burkey, Justin C. Moser, Asad Javed, Hibba tul Rehman, Mustafa Ege Seker, Alexander Birbrair, Orhan S. Ozkan, Mark R. Albertini, Yana G. Najjar, Rajan P. Kulkarni   +12 more
wiley   +1 more source

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

Frontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +14 more
doaj   +1 more source

Occurrence and Role of Selected RNA-Viruses as Potential Causative Agents of Watery Droppings in Pigeons

Pathogens, 2020
The diseases with watery droppings (diarrhea and/or polyuria) can be considered some of the most severe health problems in domestic pigeons of various ages.
Ewa Łukaszuk, Tomasz Stenzel
doaj   +1 more source

Reduced SH3RF3 May Protect Against Alzheimer's Disease by Lowering Microglial Pro‐Inflammatory Responses via Modulation of JNK and NFkB Signaling

Glia, Volume 74, Issue 7, July 2026.
SNPs in SH3RF3 decrease the age of onset of Alzheimer's disease (AD). Reduced SH3RF3 blunts human microglial JNK and NFkB signaling and downstream inflammatory cytokine production, which may partially explain how SH3RF3 SNPs protect against AD. ABSTRACT Understanding how high‐risk individuals are protected from Alzheimer's disease (AD) may illuminate ...
Ronak Patel, Rong Cheng, Christopher L. Cardona, Ellen Angeles, Gunjandeep Singh, Sabrina Miller, Archana Ashok, Andrew F. Teich, Angel Piriz, Aleyda Maldonado, Ivonne Z. Jiménez‐Velázquez, Richard Mayeux, Joseph H. Lee, Andrew A. Sproul   +13 more
wiley   +1 more source