Results 61 to 70 of about 26,015 (214)

Identification of the pocket factors in a picornavirus

Archives of Virology, 2003
Bovine enterovirus (BEV), along with other enteroviruses and the rhinoviruses, has a hydrophobic pocket within structural protein VP1. In the crystal structures of these viruses there is electron density commensurate with a non-protein molecule within the pocket.
Smyth, M.S., Martin, Jan H., Pettitt, T., Symonds, A.   +3 more
openaire   +4 more sources

Seizures following picornavirus infection [PDF]

Epilepsia, 2008
Summary Purpose: We demonstrate the establishment and characterization of a novel virus infection‐induced seizure model in C57BL/6 mice. Methods: C57BL/6 mice were infected with Theiler's murine encephalomyelitis virus (TMEV) or mock infected.
Jane E, Libbey, Nikki J, Kirkman, Matthew C P, Smith, Tomoko, Tanaka, Karen S, Wilcox, H Steve, White, Robert S, Fujinami   +6 more
openaire   +2 more sources

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti‐Tumoral Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther, Vincent Mittelheisser, Marie‐Christine Claudepierre, Louis Bochler, Magali Rompais, Jules Deforges, Nathalie Silvestre, Annabel Larnicol, Christine Carapito, Eric Quémeneur, Jacky G Goetz, Karola Rittner, Vincent Hyenne   +12 more
wiley   +1 more source

Picornavirus IRES elements: RNA structure and host protein interactions

, 2016
© 2015 Elsevier B.V. Internal ribosome entry site (IRES) elements were discovered in picornaviruses. These elements are cis-acting RNA sequences that adopt diverse three-dimensional structures and recruit the translation machinery using a 5' end ...
Martínez-Salas, Encarnación, Francisco-Velilla, Rosario, Lozano, Gloria, Fernández-Chamorro, Javier, Díaz-Toledano, Rosa   +4 more
core   +1 more source

Noncanonical Poly(A) Polymerase TENT4 Drives Expression of Subgenomic Hepatitis A Virus RNAs in Infected Cells

Viruses
Both hepatitis B virus (HBV), an hepadnavirus with a DNA genome, and hepatitis A virus (HAV), a picornavirus, require the TRAMP-like host ZCCHC14-TENT4 complex for efficient replication.
You Li, Ankit Gupta, Brian N. Papas, David Aponte-Diaz, Jayden M. Harris, Ichiro Misumi, Jason K. Whitmire, Craig E. Cameron, Marcos Morgan, Stanley M. Lemon   +9 more
doaj   +1 more source

Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

Microbiology Spectrum, 2022
Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory tract or the ...
Leanne C. Helgers, Michel S. Bhoekhan, Dasja Pajkrt, Katja C. Wolthers, Teunis B. H. Geijtenbeek, Adithya Sridhar   +5 more
doaj   +1 more source

Impact of Respiratory Viral Codetections on RSV Disease Burden in Young Children in Primary Care

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Background Young children with respiratory syncytial virus (RSV) often have viral coinfections. This study assessed the impact of respiratory viral codetections on RSV disease burden in children < 5 years and whether this varies by specific codetected viruses.
Levi Duijst, Valérie Sankatsing, Caterina Rizzo, Francesco Baglivo, Elizabeth Button, Marta Carballal Mariño, María Garcés Sánchez, Christine Hagemann, Simon de Lusignan, Oliver Martyn, Marc Raes, Daan Van Brusselen, Joanne Wildenbeest, Sarah Hak, Foekje Stelma, Jojanneke van Summeren, on behalf of the RSV ComNet network   +16 more
wiley   +1 more source

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

Frontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +14 more
doaj   +1 more source

Occurrence and Role of Selected RNA-Viruses as Potential Causative Agents of Watery Droppings in Pigeons

Pathogens, 2020
The diseases with watery droppings (diarrhea and/or polyuria) can be considered some of the most severe health problems in domestic pigeons of various ages.
Ewa Łukaszuk, Tomasz Stenzel
doaj   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source