Results 71 to 80 of about 32,243 (222)

Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

Microbiology Spectrum, 2022
Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory tract or the ...
Leanne C. Helgers, Michel S. Bhoekhan, Dasja Pajkrt, Katja C. Wolthers, Teunis B. H. Geijtenbeek, Adithya Sridhar   +5 more
doaj   +1 more source

Equine rhinitis B viruses in horse fecal samples from the Middle East [PDF]

, 2016
published_or_final_versio
CHOI, KY, Elizabeth, SK, Huang, Y, Joseph, S, Lau, SKP, Li, T, Patteril, NA, Wernery, R, Wernery, U, Wong, YM, Woo, PCY, Yuen, KY   +11 more
core   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Picornavirus RNA Recombination Counteracts Error Catastrophe [PDF]

Journal of Virology, 2019
Positive-strand RNA viruses produce vast amounts of progeny in very short periods of time via template-dependent RNA replication mechanisms. Template-dependent RNA replication, while efficient, can be disadvantageous due to error-prone viral polymerases. The accumulation of mutations in viral RNA genomes leads to error catastrophe.
Brian J, Kempf, Colleen L, Watkins, Olve B, Peersen, David J, Barton   +3 more
openaire   +2 more sources

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

Frontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +14 more
doaj   +1 more source

Occurrence and Role of Selected RNA-Viruses as Potential Causative Agents of Watery Droppings in Pigeons

Pathogens, 2020
The diseases with watery droppings (diarrhea and/or polyuria) can be considered some of the most severe health problems in domestic pigeons of various ages.
Ewa Łukaszuk, Tomasz Stenzel
doaj   +1 more source

New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features [PDF]

, 2007
BACKGROUND: Human rhinoviruses (HRV), the most frequent cause of respiratory infections, include 99 different serotypes segregating into two species, A and B.
Caroline Tapparel, Thomas Junier, Daniel Gerlach, Samuel Cordey, Sandra Van Belle, Luc Perrin, Evgeny M Zdobnov, Laurent Kaiser   +7 more
core   +2 more sources

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

Heat shock protein 90 chaperone activity is required for hepatitis A virus replication

Journal of Virology
HSP90 heat shock chaperones are essential for maintaining cellular proteostasis, as well as the ATP-dependent folding and functional maturation of many viral proteins. As a result, inhibitors of HSP90 have broad antiviral activity, disrupting replication
You Li, Xin Zheng, Ling Xie, Maryna Kapustina, Takayoshi Shirasaki, Bryan Yonish, Xian Chen, Asuka Hirai-Yuki, Noriyo Nagata, Ryosuke Suzuki, Masanori Isogawa, Matthew R. Vogt, Masamichi Muramatsu, Stanley M. Lemon   +13 more
doaj   +1 more source

Virome Variation during Sea Star Wasting Disease Progression in Pisaster ochraceus (Asteroidea, Echinodermata)

Viruses, 2020
Sea star wasting disease (SSWD) is a condition that has affected asteroids for over 120 years, yet mechanistic understanding of this wasting etiology remains elusive.
Ian Hewson, Citlalli A. Aquino, Christopher M. DeRito   +2 more
doaj   +1 more source