Results 81 to 90 of about 32,243 (222)

Quantification and Genetic Analysis of Salivirus/Klassevirus in Wastewater in Arizona, USA [PDF]

, 2016
Salivirus/klassevirus sequences were identified in 7 (15 %) wastewater samples collected in Arizona monthly for a year, with the highest concentration of 2.28 × 105 and 2.46 × 104 copies/L in influent and effluent, respectively.
Gerba, Charles P., Haramoto, Eiji, Iker, Brandon C., Kitajima, Masaaki, Rachmadi, Andri T.   +4 more
core   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, Volume 2, Issue 1, Page 106-129, March 2026.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

The Importance of Solution Studies for the Structural Characterization of the Enterovirus 5’ Cloverleaf

Viruses
Enteroviruses initiate genomic replication via a highly conserved mechanism that is controlled by an RNA platform, also known as the 5’ cloverleaf (5’CL).
Morgan G. Daniels, Meagan E. Werner, Xiaobing Zuo, Steven M. Pascal   +3 more
doaj   +1 more source

Virus‐Dependent Geographic Structure of Co‐Circulating Viruses in a Single Bat Species

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Understanding the spatial spread of viruses within wildlife populations is often a key component of disease management efforts. Viral spread is likely constrained by host ecology, but inter‐virus differences in infection strategy might allow some viruses to overcome these constraints, leading to divergent population structures within a common ...
Avery L. Holmes, Alice Broos, Daniel J. Becker, Jorge E. Carrera, Maxwell J. Farrell, Rita Ribeiro, Carlos Tello, Laura M. Bergner, Daniel G. Streicker   +8 more
wiley   +1 more source

Insights into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate. [PDF]

, 2010
Accepted ...
Allaire, Belsham, Belsham, Bergmann, Birtley, Birtley, Bjorndahl, Blom, Brunger, Brünger, Carrillo, Cordingley, Cordingley, Curry, Curry, Delano, Ellard, Frigerio, Fujinaga, Graham J. Belsham, Grubman, Grubman, Hedstrom, Hodis, Huber, Jaulent, Jewell, Jingjie Yang, Jones, Laskowski, Lee, Li, Long, Matthews, Matthews, McCoy, Mosimann, Nayak, Núria Roqué-Rosell, Pallai, Patricia A. Zunszain, Perona, Perona, Perona, Phan, Prasad, Reid, Robin J. Leatherbarrow, Schechter, Seipelt, Skern, Stephen Curry, Stephen R. Knox, Sutmoller, Sweeney, Trevor R. Sweeney, Tsunogae, Xue, Yin, Yin   +59 more
core   +1 more source

Meiosis‐specific protein co‐expression in Arabidopsis thaliana: a protein delivery tool in meiotic cells

The Plant Journal, Volume 125, Issue 6, March 2026.
SUMMARY Meiosis is a key process in sexual reproduction, orchestrated by numerous proteins that differ in their spatiotemporal expression level and dynamics. Employing meiotic gene promoters typically leads to varying levels of transgene expression within meiotic and non‐meiotic cells in plants.
Ewa W. Piskorz, Stefan Steckenborn, Maria Cuacos, Stefan Heckmann   +3 more
wiley   +1 more source

Surgical Induction of Mid‐Thoracic Aortic Coarctation in Mice: A Reproducible Preclinical Model of Pressure‐Induced Vascular Remodeling

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract Elevated arterial pressure is a key contributor to cardiovascular disease, yet experimental models that isolate the effects of pressure from confounding systemic factors remain limited. We describe a reproducible surgical protocol to induce mid‐thoracic aortic coarctation in mice, generating a stable and quantifiable arterial pressure gradient
D. Adam Lauver, Hannah Garver, Teresa Kreiger‐Burke, C. Javier Rendón, G. Andres Contreras, Stephanie W. Watts, Gregory D. Fink   +6 more
wiley   +1 more source

Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: Isolation and characterization of viable and nonviable mutants [PDF]

, 1988
By following a strategy of genetic analysis of poliovirus, we have constructed a synthetic "mutagenesis cartridge" spanning the genome-linked viral protein coding region and flanking cleavage sites in an infectious cDNA clone of the type 1 (Mahoney ...
Dunn, John J., Kuhn, Richard J., Semler, Bert L., Tada, Hiroomi, Wimmer, Eckard, Ypma-Wong, Mary Frances   +5 more
core  

Main Protease From SARS‐CoV‐2 Dysregulates Glucose Handling in the C2C12 Cell Line In Vitro: A Mechanistic Study

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background There is evidence demonstrating the risk of developing diabetes mellitus because of SARS‐CoV‐2 infection. Therefore, further research is needed to determine pathological mechanisms at which SARS‐CoV‐2 induces diabetes mellitus. This study therefore aims to understand the effect of SARS‐CoV‐2 Main protease (Mpro) on glucose uptake ...
Praise Tatenda Nhau, Mlindeli Gamede, Andile Khathi, Ntethelelo Sibiya   +3 more
wiley   +1 more source

Rhinovirus Infects B and CD4 T Lymphocytes in Hypertrophic Tonsils in Children

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Prolonged detection of rhinovirus (RV) in secretions after a typical cold and asymptomatic shedding are frequently reported. Although RV has been detected in human hypertrophic tonsils, its replicative status and host cell range remain unclear.
Ronaldo Martins, Flavia E. de Paula, Talita B. G. Mitchell, Miria F. Criado, Ricardo S. Cardoso, Bruna L. S. Jesus, Italo A. Castro, Murilo Henrique Anzolini Cassiano, Daniela Méria Ramos Rodrigues, Noilson Oliveira, Lucas Carenzi, Fabiana C. Valera, Edwin Tamashiro, Wilma T. Anselmo‐Lima, Eurico Arruda   +14 more
wiley   +1 more source