Results 91 to 100 of about 32,243 (222)

Translational Control of the Picornavirus Phenotype [PDF]

Molecular Biology, 2001
Picornaviruses are small animal viruses with positive-stranded genomic RNA, which is translated using cap-independent internal translation initiation. The key role in this is played by cis elements of the 5'-untranslated region (5'-UTR) and, in particular, by the internal ribosome entry site (IRES).
openaire   +3 more sources

Biological Function and Application of Picornaviral 2B Protein: A New Target for Antiviral Drug Development

Viruses, 2019
Picornaviruses are associated with acute and chronic diseases. The clinical manifestations of infections are often mild, but infections may also lead to respiratory symptoms, gastroenteritis, myocarditis, meningitis, hepatitis, and poliomyelitis, with ...
Zengbin Li, Zixiao Zou, Zeju Jiang, Xiaotian Huang, Qiong Liu   +4 more
doaj   +1 more source

Human rhinovirus infections in symptomatic and asymptomatic subjects [PDF]

, 2012
The role of rhinovirus asymptomatic infections in the transmission among close contacts subjects is unknown. We tested health care workers, a pair of one child and a family member and immunocompromised patients (n =191).
Bellei, Nancy Cristina Junqueira, Camargo, Clarice Neves, Carraro, Emerson, Granato, Celso Francisco Hernandes   +3 more
core   +2 more sources

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du, Yuqing Xiao, Manman Hu, Jinhua Yang, You Li, Taiyun Wei   +5 more
wiley   +1 more source

The Contribution of Microglia and Brain-Infiltrating Macrophages to the Pathogenesis of Neuroinflammatory and Neurodegenerative Diseases during TMEV Infection of the Central Nervous System

Viruses
The infection of the central nervous system (CNS) with neurotropic viruses induces neuroinflammation and is associated with the development of neuroinflammatory and neurodegenerative diseases, including multiple sclerosis and epilepsy.
Ana Beatriz DePaula-Silva
doaj   +1 more source

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns [PDF]

, 2005
DNA microarrays may be used to identify microbial species present in environmental and clinical samples. However, automated tools for reliable species identification based on observed microarray hybridization patterns are lacking. We present an algorithm,
Urisman, Anatoly, Fischer, Kael F, Chiu, Charles Y, Kistler, Amy L, Beck, Shoshannah, Wang, David, DeRisi, Joseph L   +6 more
core   +1 more source

Role of the Choline‐Binding Protein A in the Ability of Porcine Ligilactobacillus salivarius FFIG58 to Modulate TLR3‐Mediated Intestinal Antiviral Immunity

Food Frontiers, Volume 7, Issue 1, January 2026.
The choline‐binding protein A (CbpA) was shown to mediate adhesion of probiotic Ligilactobacillus salivarius strains to human intestinal epithelial cells (IECs). A knockout mutant lacking the CbpA protein derived from the immunomodulatory porcine strain L. salivarius FFIG58 was obtained. The CbpA is a key surface protein of L.
Yoshiya Imamura, Hikari Yamamuro, Mariano Elean, Lorena Paola Arce, Ryutaro Funabashi, Fernanda Raya Tonetti, Kohtaro Fukuyama, Mikado Tomokiyo, Fu Namai, Sudeb Saha, Wakako Ikeda‐Ohtsubo, Keita Nishiyama, Julio Villena, Haruki Kitazawa   +13 more
wiley   +1 more source

Structure and function of type IV IRES in picornaviruses: a systematic review

Frontiers in Microbiology
The Picornaviridae is a family of icosahedral viruses with single-stranded, highly diverse positive-sense RNA genomes. Virions consist of a capsid, without envelope, surrounding a core of RNA genome.
Yan Li, Yan Li, Lei Zhang, Ling Wang, Jing Li, Yanwei Zhao, Fuxiao Liu, Qianqian Wang   +7 more
doaj   +1 more source

Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.

PLoS ONE, 2015
Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence.
Danielle N Renner, Fang Jin, Adam J Litterman, Alexis J Balgeman, Lisa M Hanson, Jeffrey D Gamez, Michael Chae, Brett L Carlson, Jann N Sarkaria, Ian F Parney, John R Ohlfest, Istvan Pirko, Kevin D Pavelko, Aaron J Johnson   +13 more
doaj   +1 more source

Bovine Rhinitis B Virus Variant as the Putative Cause of Bronchitis in Goat Kids

Viruses
A diagnostic investigation into an outbreak of fatal respiratory disease among young goats in Iowa, USA revealed bronchitis lesions of unknown etiology and secondary bacterial bronchopneumonia.
Andrew Noel, Jianqiang Zhang, Huigang Shen, Anugrah Saxena, Jennifer Groeltz-Thrush, Ganwu Li, Michael C. Rahe   +6 more
doaj   +1 more source