Role of HER2neu expression in gastric cancer
Indian Journal of Pathology and Microbiology, 2021 Background: Gastric cancer is one of the most common cancers in the world and is responsible for over a million deaths. Gastric cancer broadly consists of two main histological types, diffuse and intestinal, and can be further classified as proximal ...
J S Sukanya +2 more
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Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers [PDF]
BMC Research Notes, 2018 Objective Her2neu receptor is proto-oncogene which can be over-expressed in both luminal and non-luminal breast cancers. In the present study, we aimed to compare the prognostic and predictive factors like tumor grade, T-stage, N-stage and ki67 index in ...
Atif Ali Hashmi +9 more
doaj +3 more sources
Societal Costs and Benefits of Treatment with Trastuzumab in Patients with Early HER2neu-Overexpressing Breast Cancer in Singapore [PDF]
BMC Cancer, 2011 Background Trastuzumab has revolutionized the way we treat early Her2Neu-positive breast cancer, as it significantly improves disease-free and overall survival.
Gilberto de Lima Lopes
core +5 more sources
Trichorhinophalangeal syndrome type 1 (TRPS1) in breast pathology: diagnostic utility and pitfalls [PDF]
Diagnostic PathologyIntroduction Breast cancer, especially triple-negative breast cancer (TNBC), lacks sensitive and specific diagnostic markers that can reliably differentiate it from carcinomas of other origins.
Atif Ali Hashmi +2 more
doaj +2 more sources
Targeted therapies in primary vaginal cancer [PDF]
Journal of Cancer Research and Clinical OncologyObjective Primary vaginal cancer (PVC) accounts for 1–2% of all gynecological malignancies. Therefore, clinical trials lack and there is a paucity of approved medications beyond radiation or chemoradiation as main first line therapy.
Laura Tascón Padrón +7 more
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[Neuroendocrine expression markers in triple-negative, luminal-A, luminal-B and HER2neu breast cancer]. [PDF]
Rev Med Inst Mex Seguro Soc, 2023 Primary breast tumors with neuroendocrine (NE) differentiation are a heterogeneous tumor group with diversity of biological behavior, with poorly defined prevalence and prognosis.To evaluate the chromogranin, synaptophysin, CD56, INSM1 markers expression prevalence and the association between NE differentiation and tumor molecular type.Observational ...
Barboza-García YG +4 more
europepmc +4 more sources
The significance of expression of Her2neu in squamous cell carcinoma of uterine cervix [PDF]
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2019 Background: Cervical cancer is one of the leading causes of cancer related deaths among females. It arises from precursor lesions i.e. squamous intraepithelial lesions which are closely associated with infection by HPV.
Sarin, Namrata +3 more
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Clinicopathological Significance and Prognostic Role of Her2neu Protein Expression in Patients with Carcinoma Stomach: A Prospective Study from Northern India [PDF]
South Asian Journal of Cancer, 2023 Abhilash V. B. +4 more
doaj +2 more sources
Human Leukocyte Antigen Class I Expression and Natural Killer Cell Infiltration and Its Correlation with Prognostic Features in Luminal Breast Cancers [PDF]
Breast Cancer: Targets and TherapyMaria Vernet-Tomas,1,2 Ivonne Vazquez,1,3 Francesc Olivares,3 David Lopez,3 Jose Yelamos,2,4 Laura Comerma1– 3 1Breast Diseases Unit, Hospital Del Mar, Barcelona, Spain; 2Cancer Research Program, Hospital del Mar Medical Research Institute (IMIM ...
Vernet-Tomas M +5 more
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Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer [PDF]
, 2012 Introduction The presence of circulating tumor cells (CTC) is an independent prognostic factor for progression-free survival and breast cancer-related death (BRD) for patients with metastatic breast cancer beginning a new line of systemic therapy.
Arjan GJ Tibbe +6 more
core +23 more sources