Results 11 to 20 of about 2,976 (190)

Prognostic implications of HER2NEU‐low in metastatic breast cancer

Cancer Medicine
AbstractIntroductionWe explored characteristics and clinical outcomes of HER2‐negative and HER2‐low metastatic breast cancers using real‐world data.MethodsWe queried the National Cancer Database to identify MBC patients that were HER2‐low or HER2‐negative per immunohistochemical staining.
Zachary Neubauer, Shaakir Hasan, Robert H. Press, Arpit M. Chhabra, Jana Fox, Richard Bakst, Charles B. Simone, J. Isabelle Choi   +7 more
openaire   +3 more sources

Breast Cancer Heterogeneity in Latin America: A Scoping Review of Clinical-Pathological Characteristics, Molecular Subtypes, and Survival. [PDF]

World J Surg
Breast cancer in Latin America (LATAM) exhibits distinct clinical‐pathological and molecular features, shaped by genetic diversity and healthcare disparities. This scoping review evaluates these characteristics, focusing on histopathological, molecular subtype and survival patterns and their implications for future research and public health ...
Aponte-Rueda ME, Gómez-González FM, Merck B.   +2 more
europepmc   +2 more sources

Programmed Death Ligand 1 (PDL1) Expression in Neoadjuvant Triple-Negative Breast Cancer: Association With Chemotherapy Response and Residual Cancer Burden. [PDF]

Breast J
Background Programmed death ligand 1 (PDL1) expression in tumors is linked to immune evasion in various cancers, making these patients potential candidates for PDL1 inhibitors. Although immune checkpoint blockade therapy has gained approval for breast cancer treatment, especially triple‐negative breast cancer (TNBC), there is a lack of PDL1 expression ...
Hashmi AA, Wahid N, Mudassir G, Irfan M, Malik UA, Khan EY, Abu Bakar SM, Faridi N.   +7 more
europepmc   +2 more sources

Evaluation of CD9 Expression of Tumour Cells and Stromal Immune Cells in Breast Carcinoma by Immunohistochemistry [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Cluster of Differentiation 9 (CD9), known as Motility Related Protein (MRP-1) regulates cell adhesion, motility, migration and proliferation.
RV Sowjanya Lakshmi, ML Harendra Kumar, K Mohan Kumar   +2 more
doaj   +1 more source

Predictive Value of Excision Repair Cross Complementation Group 1 (ERCC1) by Immunohistochemistry for Determining Neoadjuvant Chemotherapy Response in Triple-Negative Breast Cancers. [PDF]

Breast J
Introduction: Triple‐negative breast cancers (TNBCs) constitute a significant proportion of breast cancers in Pakistan. Owing to the lack of expression of hormone (estrogen/progesterone) receptor and human epidermal growth factor receptor 2 (HER2neu), treatment options for TNBCs are limited.
Hashmi AA, Ajaz Y, Sajjad M, Zia F, Irfan M, Abu Bakar SM, Khan EY, Faridi N.   +7 more
europepmc   +2 more sources

Her2neu Expression of Gastric and Lower Esophageal Carcinoma and its Correlation with Clinicopathological Findings in Tertiary Care Hospital in Eastern India

Biomedical and Biotechnology Research Journal, 2022
Background: Gastric carcinomas are the fifth most common cancer worldwide and cause the second most common cancer-related deaths. Human epidermal growth factor receptor 2 (HER-2/Neu)(c-erbB2) protein overexpression in gastric cancer has been correlated ...
Dipsikha Chakraborty, Sanchita Ghosh, Bhawna Bhutoria Jain, Saurav Kumar Ghosh, Ayandip Nandi   +4 more
doaj   +1 more source

A clinical case of cardioprotective therapy with exogenous phosphocreatine during chemotherapy and anti HER2-neu therapy in a patient with breast cancer

Клинический разбор в общей медицине, 2023
The authors describe a clinical observation of cardiotoxicity of anticancer targeted therapy in a young patient with HER2neu-positive breast cancer. The results of instrumental examinations demonstrating manifestations of cardiotoxicity are presented ...
Andrey L. Pylev, Vyacheslav A. Lisovoy, Olga S. Kozlova   +2 more
doaj   +1 more source

Her2neu Amplification Associates with Co-deletion 1p/14q in Recurrent Meningiomas [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2013
Background:The current methods to predict recurrence and aggressive behaviour of meningiomas rely mainly on histological grading, histological subtype, proliferative index, as well as brain invasion. In many instances, histological grade alone fails to predict recurrence in the grade I and grade II meningiomas.
Brenda O, Hamilton, Joanne S, Sy, Joseph F, Megyesi, Lee Cyn, Ang   +3 more
openaire   +2 more sources

Expression of Her2Neu in gastric adenocarcinoma: An institutional study

Panacea Journal of Medical Sciences, 2021
Introduction: Trastuzumab has been recently proposed as a treatment for patients with HER2-positive advanced/metastatic gastric cancer. Since most patients have inoperable disease at diagnosis, accurate assessment of HER2 status on biopsy specimens is essential to select the patients who may benefit from therapy.
Prasanta K Das, Sagarika Panda*, Manoj K Patro, Gitashree Mishra   +3 more
openaire   +1 more source

Breast cancer imaging features as a predictor of the hormonal receptor status, HER2neu expression and molecular subtype

The Egyptian Journal of Radiology and Nuclear Medicine, 2020
Background Determination of the hormonal receptor (HR) status, HER2neu expression, and the molecular subtype has valuable diagnostic, therapeutic, and prognostic implications for breast cancer as breast cancer stratification during the last two decades ...
Maged Abdelfattah Ali Algazzar, Elsayed El-Mekkawy Elsayed, Alshimaa Mahmoud Alhanafy, Waleed Abdelfattah Mousa   +3 more
doaj   +1 more source