Results 81 to 90 of about 2,976 (190)

Pattern of oestrogen, progesterone and Her2neu receptors expression in a heterogeneous carcinoma of the breast in a lactating woman [PDF]

BMJ Case Reports, 2010
Oestrogen-progestrone-Her2neu receptor status was studied in various loci/foci of heterogeneous carcinoma of the breast and its metastatic secretory component in the lymph node in a lactating woman. All the carcinoma variants were negative for the trio markers except tumour components evolved to secretory or lactating carcinoma, which showed focal ...
Mohammed, Naim, Amit, Kumar, Kavita, Gaur, Vanesa T, John   +3 more
openaire   +2 more sources

Tomotherapy in synchronous and metachronous bilateral breast cancer: Clinical experience

Journal of Applied Clinical Medical Physics, Volume 25, Issue 7, July 2024.
Abstract Purpose of study The objective of this research is to present our firsthand experience and provide up‐to‐date data for the further study of cases involving simultaneous breast irradiation using helical Tomotherapy, ©Accuray Inc. Methods The radical treatment options for bilateral breast cancer are surgery, chemotherapy, and radiation therapy ...
Yernar Orda, Tanzhas Shayakhmetov, Saniya Baiturova, Daulet Berikbol, Rauan Otynshiyev, Aigul Brimova, Bolat Saktashev, Ainur Baisalbayeva, Ainur Samigatova   +8 more
wiley   +1 more source

A Genome‐Wide Association Study of Endoxifen Serum Concentrations and Adjuvant Tamoxifen Efficacy in Early‐Stage Breast Cancer Patients

Clinical Pharmacology &Therapeutics, Volume 116, Issue 1, Page 155-164, July 2024.
Tamoxifen is part of the standard of care of endocrine therapy for adjuvant treatment of breast cancer. However, survival outcomes with tamoxifen are highly variable. The concentration of endoxifen, the 30–100 times more potent metabolite of tamoxifen and bioactivated by the CYP2D6 enzyme, has been described as the most relevant metabolite of tamoxifen
Anabel Beatriz Sanchez‐Spitman, Stefan Böhringer, Vincent Olaf Dezentjé, Hans Gelderblom, Jesse Joachim Swen, Henk‐Jan Guchelaar   +5 more
wiley   +1 more source

CD10-A new prognostic stromal marker in breast carcinoma, its utility, limitations and role in breast cancer pathogenesis

Indian Journal of Pathology and Microbiology, 2014
Background and Aims: Breast cancer is one of the leading causes of mortality in Indian women. Although breast cancer is an epithelial malignancy, stroma plays a key role in its development and pathogenesis.
Sayantan H Jana, Bharti M Jha, Chandni Patel, Dipan Jana, Anshul Agarwal   +4 more
doaj   +1 more source

Curatieve resectie van solitaire claviculametastase [PDF]

, 2014
Achtergrond Het gemetastaseerd mammacarcinoom wordt beschouwd als niet-curabele ziekte waarbij patiënten alleen in aanmerking komen voor palliatieve systemische behandeling. Bij geselecteerde patiënten met beperkte metastasen wordt echter langdurige
Mureau, M.A.M. (Marc), Obdeijn, A.I.M. (Inge-Marie), Rothbarth, Ph.H. (Philip), Seynaeve, C.M. (Caroline), Verhofstad, M.H.J. (Michiel), Vos, E.L. (Elvira)   +5 more
core  

Pure mucinous adenocarcinoma of the breast with the rare lymphoplasmacytic infiltration: A case report with review of literature

Clinical Case Reports, Volume 12, Issue 4, April 2024.
Shows the progression of the patient pre operative to after the procedure (Lumpectomy) was performed. Key Clinical Message A unique ER/PR‐positive mucinous adenocarcinoma of breast but CK7/CK20 negativity. A rare finding of Lymphoplasmacytic Infiltration is noted.
Yash Hasmukhbhai Prajapati, Vishal Bhabhor, Kahan Samirkumar Mehta, Mithoon Barot, Husen Boriwala, Mohamed Omar   +5 more
wiley   +1 more source

Comparing the Prognostic Value of PTEN and Akt Expression with the Mitotic Activity Index in Adjuvant Chemotherapy-Treated Node-Negative Breast Cancer patients aged <55 years

Cellular Oncology, 2007
Background: The prognostic value of the PI3K/Akt/mTOR pathway and PTEN in invasive breast cancer (IBC) is controversial. Cell proliferation, especially the Mitotic Activity Index (MAI), is strongly prognostic in lymph node-negative (LNneg) invasive ...
Emiel A. M. Janssen, Håvard Søiland, Ivar Skaland, Einar Gudlaugson, Kjell H. Kjellevold, Arne Nysted, Jon-Arne Søreide, Jan P. A. Baak   +7 more
doaj   +1 more source

Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne

Cancer Medicine, Volume 13, Issue 3, February 2024.
TP53‐associated tumor syndrome is a rare predisposition syndrome. Our analysis of the tumor spectrum and age of onset in 35 index patients supports the evidence for a less severe phenotype in families identified by gene panel testing for hereditary breast and ovarian cancer. Abstract Purpose Tumor protein p53 (TP53) pathogenic variant (PV) carriers are
K. Kast, K. Rhiem, M. Larsen, B. Wappenschmidt, R. Schmutzler   +4 more
wiley   +1 more source

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC [PDF]

, 2014
In head and neck squamous cell cancer (HNSCC), four intrinsic subtypes (or groups) have been identified, and each one possesses a unique biology that will require specific treatment strategies.
Adkins, Douglas, Chung, Christine H., Ellis, Matthew J., Fertig, Elana J., Herrlich, Andreas, Jones, Lamont, Kimple, Randall J., Lewis, James, Lim, Sora, Maher, Christopher A., Michel, Loren S., Van Tine, Brian A., Zhang, Kaihua   +12 more
core   +3 more sources

Assessment of Tissue Eosinophilic Infiltration in Invasive Mammary Carcinoma

International Journal of Breast Cancer, Volume 2024, Issue 1, 2024.
Background: Stromal inflammatory cells in malignant tissue have recently gained increasing interest. Unlike the extensive research on tumor‐infiltrating lymphocytes, published data about tumor‐infiltrating eosinophils in breast cancer are scarce. Furthermore, similar studies have yet to be conducted in Iraq.
Farah Falah Hasan, Mohammed Haider Fadhil, Zainab Khalid Almukhtar, Ivana Ribeiro   +3 more
wiley   +1 more source