Results 31 to 40 of about 174,972 (245)

Anti-obesity activity of Cymbopogon citratus (lemongrass): A systematic review [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Obesity represents a significant global health challenge. The limited efficacy and possible side effects of available anti-obesity agents highlight the need to find new, effective, and safe agents. Lemongrass (Cymbopogon citratus) is an aromatic
Musthika Wida Mashitah, Nashi Widodo, Nur Permatasari, Achmad Rudijanto   +3 more
doaj   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

The effect of ethanol-based coriander (Coriandrum sativum L.) seed extract on oxidative stress, antioxidant level and cellular senescence in the heart of obese rat [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: High-fat diets contribute to oxidative stress and trigger cellular senescence through an imbalance in reactive oxygen species. The potential of coriander (Coriandrum sativum) seed, known for its therapeutic properties against oxidative stress ...
Irah Namirah, Kayla S. Wimbanu, Albertus M.E. Rompies, Yosafat S. Prayogo, Wawaimuli Arozal, Fadilah, Muhammad Hanafi, Novi S. Hardiany   +7 more
doaj   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Comparative evaluation of herbal extract-containing mouthwash on periodontal parameters: A randomized controlled trial

SRM Journal of Research in Dental Sciences
Background: Plaque is the main causative agent in the onset and progression of periodontal diseases and is directly linked to the development of gingivitis.
Harsh D. Borundia, Surekha Rathod, Savita Sharma, Shivani Koli   +3 more
doaj   +1 more source

A comparative study of the chemical composition and antioxidant capacity of the essential oils from three species of Mentha cultivated in Morocco [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Mentha species are well known for their health benefits. Products extracted from aromatic plants of this genus (Mentha) are increasingly being studied for their active constituents in order to replace synthetic products that are harmful to ...
Arrahmouni Rayan, Ouazzani Chadia, Er-Ramly Azzedine, Moustaghfir Abdellah, Benchama Zakaria, Elamrani Abdelaziz, Benkhouili Fatima Zahra, El-Guourrami Otman, Dami Abdallah, Balouch Lhousaine   +9 more
doaj   +1 more source

The prevalence, risk factors and lifestyle patterns of Jordanian females with premenstrual syndrome: a cross-sectional study

Future Science OA, 2023
Aim: The study aims to assess factors associated with premenstrual syndrome (PMS) and the frequency of using painkillers to relieve premenstrual pain. Methods: This is a cross-sectional study of 1580 premenopausal women.
Mera A Ababneh, Malak Alkhalil, Abeer Rababa'h   +2 more
doaj   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Studies on phytochemical, antioxidant, anti-inflammatory, hypoglycaemic and antiproliferative activities of Echinacea purpurea and Echinacea angustifolia extracts

Pharmaceutical Biology, 2017
Context: Echinacea (Asteraceae) is used because of its pharmacological properties. However, there are few studies that integrate phytochemical analyses with pharmacological effects.
Rayn Clarenc Aarland, Angel Ernesto Bañuelos-Hernández, Mabel Fragoso-Serrano, Edgar del Carmen Sierra-Palacios, Fernando Díaz de León-Sánchez, Laura Josefina Pérez-Flores, Fernando Rivera-Cabrera, José Alberto Mendoza-Espinoza   +7 more
doaj   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source