Results 61 to 70 of about 174,972 (245)

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang   +10 more
wiley   +1 more source

Integrated Assessment of Lipid Oxidation and Off‐Flavor Formation in Plant Protein Powders

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Impact of residual lipids on oxylipin and off‐flavor formation in commercial plant proteins: A detailed analysis of precursor‐product relationships by GC‐FID, LC‐MS/MS, and GC‐MS. ABSTRACT The widespread adoption of plant proteins is hindered by their inherent off‐flavors, often linked to lipid oxidation products.
Fernanda Furlan Goncalves Dias   +3 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

open access: yesAnimal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang   +11 more
wiley   +1 more source

Les savoirs sur le corps féminin dans l’Hortus sanitatis et sa traduction française

open access: yesKentron, 2013
In this article the scope and goal of the Renaissance French translation of the Hortus sanitatis will be examined. In order to provide a complete overview of the different questions raised by the text and its translation ...
Violaine Giacomotto-Charra
doaj   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

open access: yesAnimal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu   +11 more
wiley   +1 more source

REVIEW OF MODERN ADVANCED MEDICINAL PRODUCTS CONTAINING THE BIOLOGICALLY ACTIVE COMPONENTS OF CHAGA MUSHROOM BIRCH

open access: yesРазработка и регистрация лекарственных средств, 2019
Advanced products containing the biologically active components of chaga mushroom (Inonotus obliquus) have been reviewed. A great interest in chaga as a promising natural crude drug has been found.
O. Yu. Kuznetsova
doaj  

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson   +11 more
wiley   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Oral Hygiene Improvements by a Novel Zinc Toothpaste—Results from a 6-Week Randomized Clinical Study amongst Community-Dwelling Adults

open access: yesHygiene
Objective: This clinical investigation evaluated oral health improvements after the use of a novel zinc toothpaste in comparison to a control after 3 weeks and 6 weeks of use.
Prem K. Sreenivasan   +3 more
doaj   +1 more source

Perspective: Herbal dangers [PDF]

open access: yesNature, 2011
Traditional plant-based remedies are not risk-free. Doctors and patients need to be informed about the possible side effects, says Masatomo Sakurai.
openaire   +2 more sources

Home - About - Disclaimer - Privacy