Results 51 to 60 of about 76,407 (308)

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Attitude and use of herbal medicines among pregnant women in Nigeria

BMC Complementary and Alternative Medicine, 2009
Background The use of herbal medicines among pregnant women in Nigeria has not been widely studied. Methods Opinion of 595 pregnant women in three geopolitical zones in Nigeria on the use of herbal medicines, safety on usage, knowledge of potential ...
Adisa Rasaq, Fakeye Titilayo O, Musa Ismail E   +2 more
doaj   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Integrated multi-omics analysis reveals the molecular mechanism of tuber morphogenesis under different planting densities in yam (Dioscorea opposita Thunb.)

Frontiers in Plant Science
Chinese yam (Dioscorea opposita Thunb.) is a typical medicinal and edible homologous plant, whose tubers are used for food or medicine. The length and thickness of the tubers directly determine their yield and quality.
Peng Wang, Peng Wang, Guixiao La, Guixiao La, Xiangyang Li, Xiangyang Li, Dandan Dai, Dandan Dai, Guixia Shi, Guixia Shi, Yi Wen, Yi Wen, Tiegang Yang, Tiegang Yang   +13 more
doaj   +1 more source

Analysis of Polyphenolic Composition of a Herbal Medicinal Product—Peppermint Tincture

Molecules, 2019
The pharmacological activity of peppermint leaf (Menthae piperitae folium) for medical use is mainly attributed to the presence of essential oil, which, according to the European Pharmacopoeia (Ph.
Agnieszka Bodalska, Adam Kowalczyk, Maciej Włodarczyk, Izabela Fecka   +3 more
doaj   +1 more source

Herbal medicines

, 2017
This chapter is aimed at all healthcare professionals, patients, and the general public to provide a brief insight to the importance of herbal medicines.
Marc Mitchell, Nicola Stoner, Melanie Snelling, Philip Wiffen   +3 more
core   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Herbal medicine use among urban residents in Lagos, Nigeria

BMC Complementary and Alternative Medicine, 2011
Background Over three-quarter of the world's population is using herbal medicines with an increasing trend globally. Herbal medicines may be beneficial but are not completely harmless.
Oreagba Ibrahim, Oshikoya Kazeem, Amachree Mercy   +2 more
doaj   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Co-application of dazomet and azoxystrobin reconstructs soil microbial communities and suppresses the violet root rot of Codonopsis tangshen under a continuous cropping system

Microbiology Spectrum
Violet root rot (VRR) is a devastating soil-borne disease that severely affects Codonopsis tangshen (C. tangshen) production, with limited effective control strategies available.
Wuxian Zhou, Xiaofang Wang, Xiaogang Jiang, Darong Li, Meide Zhang, Daye Huang, Jie Guo, Jingmao You, Qingfang Wang   +8 more
doaj   +1 more source