Results 41 to 50 of about 314,434 (304)

How safe are herbal products? [PDF]

, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

Are herbal medicines effective in the treatment of ischemic stroke? : a systematic review of human-controlled clinical trials

, 2019
Cerebrovascular diseases are common, and stroke constitutes the third cause of death as well as the first cause of disability all over the world. Many studies have demonstrated the beneficial effects of herbal preparations on stroke.
Javan, Roghayeh, Doosti, Hassan, Ayati, Zahra (R20105), Guillemin, Gilles J., Yousefi, Mahdi, Baghdar, Hamideh N., Delshad, Elahe, Farshchi, Masoumeh K.   +7 more
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Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns [PDF]

, 2012
Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular
Michael Bunce, Haile, James, Jayne Houston, Haile James, White Nicole E., Bellgard, Matthew I., Megan L Coghlan, Paula Moolhuijzen (171379), Paula Moolhuijzen, Dáithí C. Murray (171368), Bellgard, M.I., Houston Jayne, Murray, D.C., Houston, Jayne, Dáithí C Murray, White, N.E., Coghlan, Megan L., James Haile (40135), Jayne Houston (171362), Coghlan, Megan, Bellgard Matthew I., Coghlan Megan L., Matthew I. Bellgard (171383), Coghlan, M.L., Matthew I Bellgard, Murray Dáithí C., Moolhuijzen, Paula, Megan L. Coghlan (171354), White, Nicole E., Nicole E. White (171373), Moolhuijzen, P., Haile, J., White, Nicole, Houston, J., Bellgard, M., Moolhuijzen Paula, Murray, D., Michael Bunce (31164), James Haile, Murray, Dáithí C., Nicole E White, Bunce, M., Bunce Michael, Bunce, Michael   +43 more
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Herbal remedies against Huntington's disease: Preclinical evidences and future directions

, 2022
Herbal medicines, or phytochemicals can treat various neurological disorders, and is actually preferred over synthetic drugs due to their lower cost, negligible side effects, easy availability and therapeutic efficiency.
Tudu, C.K., Nandy, S., Banerjee, S., Ghorai, M., Pandey, D.K., Bursal, Ercan, Shekhawat, M.S.   +6 more
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Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

The Effects of Pretreatment with Various Doses of L-Arginine on Cisplatin-Induced Nephropathy of Male Rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
Introduction: Cisplatin is a widely used anti-cancer drug, which its application is limited by nephrotoxicity. In this study, the effect of pretreatment with different l-arginine doses on Cisplatin-induced renal functional injury was investigated ...
B Rasoulian, N Moradi Rad, F Behrahi, M Jabari, M Rashidipour, Z Khoshdek, M Alirezaei   +6 more
doaj  

Using omics approaches to dissect the therapeutic effects of Chinese herbal medicines on gastrointestinal cancers

Frontiers in Pharmacology, 2022
Chinese herbal medicines offer a rich source of anti-cancer drugs. Differences between the pharmacology of Chinese herbal medicines and modern synthetic chemicals hinder the development of drugs derived from herbal products.
Si-Yi Li, Si-Yi Li, Si-Yi Li, Wei-Jia Wang, Qiu-Yue Li, Qiu-Yue Li, Peng-Hui Yang, Peng-Hui Yang, Xin-Long Li, Xin-Long Li, Yan Yan, Yong Yuan, Yi-Bin Feng, Ming Hong   +13 more
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Traditional/alternative medicines and the right to health : key elements for a convention on global health [PDF]

, 2013
Little has been done to investigate and promote the importance of non-conventional medicines (NCMs) in the realization of the right to health, yet all over the world people regularly resort to NCMs to secure healing or to prevent or mitigate the ...
Chastonay, Philippe, Kandala, Ngianga-Bakwin, Kandolo, Tshimungu, Bukonda, Ngoyi K. Zachari, Kabengele Mpinga, Emmanuel, Verloo, Henk   +5 more
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Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source