Results 211 to 220 of about 1,006,484 (278)

Integrated Experimental, Chemometric, and In Silico Analyses of Larvicidal Supercritical Extracts From Myrtaceae Species Against Aedes aegypti

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The cross‐validated regression tree showed modest predictive performance. Mortality was not significantly associated with the first two PCA axes. Molecular modeling generated testable ligand–target hypotheses. Psidium cattleianum had lower LD50. The larvicidal activity of the crude extracts could not be attributed to individual constituents.
Ubiratan Alegransi Bones   +8 more
wiley   +1 more source

Convolvulus althaeoides as a Potential Natural Source in Cancer Prophylaxis and Treatment: LC‐ESI‐MS/MS, GC‐MS, In Vitro, and In Silico Investigations

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
n‐hexane and EtOAc fractions of Convolvulus althaeoides aerial parts have potent cytotoxicity, significant antioxidant, and moderate anti‐inflammatory effects. These activities emphasize the potential role of this plant in cancer prophylaxis and treatment.
Ahmed R. Hassan   +4 more
wiley   +1 more source

Anti‐Inflammatory Activity of Cotula cinerea Essential Oil: Integrated Chemical, In Vivo, Histological, and Computational Evaluation

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Cotula cinerea essential oil was chemically profiled and evaluated in an exploratory in vivo model with histological assessment, while computational analyses generated hypotheses for interactions of selected constituents with COX‐2 and BSA. The predictive findings require direct experimental validation. ABSTRACT The anti‐inflammatory activity of Cotula
Habiba Haddad   +10 more
wiley   +1 more source

Phytochemical Analysis of Moroccan Mercurialis annua L. and Its Nephroprotective Activity: Evidence Supporting Traditional Renal Uses

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Mercurialis annua L.: Phytochemistry and Nephroprotective Activity. ABSTRACT Mercurialis annua L. (Euphorbiaceae) is traditionally used to treat renal disorders, although its nephroprotective activity remains poorly documented. This study characterized the phytochemical profile of the Moroccan hydroethanolic extract by UHPLC–ESI/MS, evaluated its acute
Abdeljalil Elmahdaoui   +7 more
wiley   +1 more source

Anti‐Inflammatory Effects of Vicatia thibetica De Boiss. in Rheumatoid Arthritis and Associated Multi‐Pathway Modulation In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Vicatia thibetica de Boiss. (VTDB) extracts and fractions were screened for anti‐rheumatoid arthritis activity via UHPLC‐MS, network pharmacology, and CIA rat models. VTDB‐nBuOH stood out, regulating PI3K/Akt, JAK2/STAT3, macrophage polarization, and gut microbiota to relieve joint inflammation, with proteomics verifying its multi‐pathway regulatory ...
Mo‐Zi‐Li Adu   +9 more
wiley   +1 more source

Integrated Phytochemical, Immunological, and Network Pharmacology Investigation of Anti‐Inflammatory Lignans From Zanthoxylum armatum Fruits

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Bioassay‐guided fractionation of Zanthoxylum armatum fruits identifies three bioactive lignans—sesamin, fargesin, and eudesmin. The identified lignans attenuate CpG‐induced dendritic‐cell activation by reducing IL‐12 expression and CD80. Network pharmacology and molecular docking suggest involvement of multiple inflammatory signalling pathways ...
Ningthoujam Indrajit Singh   +3 more
wiley   +1 more source

UHPLC/MS‐MS Profiling, Antioxidant and Antimicrobial Properties of Atriplex halimus L. and Marrubium deserti De Noé Extracts: In Vitro and In Silico

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the phytochemical profile and biological potential of Atriplex halimus L. and Marrubium deserti De Noé extracts. Polyphenolic constituents are identified using UHPLC‐MS/MS analysis, complemented by TPC and TFC evaluations. Antioxidant activities are determined via DPPH, ABTS, and FRAP assays, while antimicrobial efficacy is ...
Nacira Siad   +9 more
wiley   +1 more source

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