Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Hereafter comprehension of Imam Mâtüridî
Dünya hayatının son bulup sonrasında başlayacak ikinci bir hayatın adı âhiret hayatıdır. Âhiret hayatı asıl hayat olduğu gibi mahiyeti de çok tartışmalı konulardan bir tanesidir.
Akman, Hacer Hafsa
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Atom Egoyan: The Sweet Hereafter
This book contribution discusses the Canadian film 'The Sweet Hereafter' by the director Atom Egoyan.
Hutchison, David
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Wide scope of administrative discretion justified by features of telecommunications market. Case comment to the judgment of the Polish Supreme Court of 2 April 2009 – Telekomunikacja Polska SA v the President of the Electronic Communications Office (Ref. No. III SK 28/08) [PDF]
On 2 April 2009, the Polish Supreme Court (hereafter, Supreme Court or Court) delivered a judgment on the scope of power of the President of the Electronic Communications Office (hereafter, UKE) to impose obligations upon tele communications operators in
Małgorzata Kozak
doaj
Data on different seed harvesting methods used in grassland restoration on ex-arable land
We present data of the grassland restoration experiment performed in the Bílé Karpaty Mts. (White Carpathians, Czech Republic) in dry species-rich meadows.
Ágnes-Júlia Albert +7 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Is the parallel competence set out in Regulation 1/2003 totally clear? Case comment to the preliminary ruling of the Court of Justice of 3 May 2011 Tele 2 v Prezes Urzędu Ochrony Konkurencji i Konsumentów (Case C-375/09) [PDF]
With a motion dated 28th of April 2005 submitted to the President of the Office of Competition and Consumer Protection (in Polish: Prezes Urzędu Ochrony Konkurencji i Konsumentów; hereafter, UOKiK President), Tele2 Polska Sp. z o.o. (currently: Netia S.A.
Ilona Szwedziak
doaj
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

