Results 31 to 40 of about 197,953 (330)

A patient with hereditary angioedema and systemic lupus erythematosus: Coincidence or coexistence?

Medicine Science, 2020
Angioedema is classified into two major groups: mast cell-mediated (histaminergic) and bradykinin-mediated angioedema. Hereditary angioedema and acquired angioedema are well-defined groups of bradykinin-mediated angioedema. Both hereditary angioedema and
Gokhan Aytekin, Fatih Colkesen, Eray Yildiz, Sevket Arslan   +3 more
doaj   +1 more source

Assessment and management of disease burden and quality of life in patients with hereditary angioedema: a consensus report

Allergy, Asthma & Clinical Immunology, 2021
Background Hereditary angioedema (HAE) is a rare disease characterized by unpredictable, potentially life-threatening attacks, resulting in significant physical and emotional burdens for patients and families.
K. Bork, John T. Anderson, T. Caballero, T. Craig, D. Johnston, H. Li, H. Longhurst, C. Radojicic, M. Riedl   +8 more
semanticscholar   +1 more source

Successful use of lanadelumab in a patient with hereditary angioedema with normal C1 inhibitor and negative genetic testing

Journal of Allergy and Clinical Immunology: Global, 2023
We report an approximately 80% reduction in angioedema attacks with lanadelumab, a mAb targeting plasma kallikrein, in a case of hereditary angioedema with normal C1 inhibitor levels.
Adil Adatia, MD, Bruce Ritchie, MD
doaj   +1 more source

The Genetics of Hereditary Angioedema: A Review

Journal of Clinical Medicine, 2021
Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of the accumulation of fluids outside of the blood vessels, causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway.
R. Santacroce, G. D’Andrea, A. B. Maffione, M. Margaglione, M. d’Apolito   +4 more
semanticscholar   +1 more source

Hereditary Angioedema: The Clinical Picture of Excessive Contact Activation

Seminars in Thrombosis and Hemostasis, 2022
Hereditary angioedema is a rare, genetic disorder characterized by painful, debilitating and potentially life-threatening angioedema attacks in subcutaneous and submucosal tissue.
Remy S. Petersen, Lauré M. Fijen, M. Levi, D. Cohn   +3 more
semanticscholar   +1 more source

Risk of angioedema following invasive or surgical procedures in HAE type I and II : the natural history [PDF]

, 2013
Background: Hereditary angioedema (HAE), caused by deficiency in C1-inhibitor (C1-INH), leads to unpredictable edema of subcutaneous tissues with potentially fatal complications.
Aygören-Pürsün, Emel, Klingebiel, Thomas, Kreuz, Wolfhart, Martinez Saguer, Inmaculada, Schwabe, Dirk   +4 more
core   +1 more source

Long‐term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study

Allergy. European Journal of Allergy and Clinical Immunology, 2021
The aim was to evaluate long‐term effectiveness and safety of lanadelumab in patients ≥12 y old with hereditary angioedema (HAE) 1/2 (NCT02741596).
A. Banerji, J. Bernstein, D. Johnston, W. Lumry, M. Magerl, M. Maurer, I. Martínez-Saguer, A. Zanichelli, James Hao, N. Inhaber, Ming Yu, M. Riedl   +11 more
semanticscholar   +1 more source

WAO guideline for the management of hereditary angioedema [PDF]

, 2012
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel, Bork, Konrad, Bowen, Tom, Boysen, Henrik B., Craig, Timothy, Farkas, Henriette, Grumach, Anete, Katelaris, Constance H., Lockey, Richard, Longhurst, Hilary, Lumry, William, Magerl, Markus, Martinez-Saguer, Immaculada, Maurer, Marcus, Nast, Alexander, Pawankar, Ruby, Ritchie, Bruce, Zuraw, Bruce   +17 more
core   +1 more source

Clinical characteristics and burden of illness in patients with hereditary angioedema: findings from a multinational patient survey

Orphanet Journal of Rare Diseases, 2021
Background Hereditary angioedema (HAE) is a rare, debilitating, genetic disease characterized by unpredictable, recurrent, and potentially fatal swelling of the skin and mucous membranes.
J. Mendivil, R. Murphy, M. de la Cruz, E. Janssen, H. Boysen, G. Jain, E. Aygören‐Pürsün, I. Hirji, G. Devercelli   +8 more
semanticscholar   +1 more source

C1 inhibitor deficiency: 2014 United Kingdom consensus document [PDF]

, 2015
C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient ...
Ashworth, F, Bethune, C, Cale, C, Dempster, J, Edgar, D, Gompels, M, Jolles, S, Longhurst, H J, Price, A, Seneviratne, S, Symons, C, Tarzi, M D   +11 more
core   +3 more sources