Results 41 to 50 of about 16,652 (272)

Pediatric hereditary angioedema [PDF]

open access: yesPediatric Allergy and Immunology, 2013
Abstract Hereditary angioedema ( HAE ) is a lifelong illness characterized by recurrent swelling of the skin, intestinal tract, and, ominously, the upper airway. It is caused by inadequate activity of the protein C1‐inhibitor, with dysfunction in the kallikrein/bradykinin ...
openaire   +3 more sources

Hereditary angioedema: Not an allergy

open access: yesIndian Journal of Dermatology, 2012
Hereditary angioedema is a genetic disorder due to a deficiency or malfunction of C1 esterase inhibitor. We herein describe a case of 25-year-old male who presented with swelling over face since one day.
Sanjay Bhivgade   +3 more
doaj   +1 more source

Remission of hereditary angioedema attacks associated with starting teriflunomide in a patient with multiple sclerosis

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Background: Hereditary angioedema is a rare hereditary and potentially life-threatening disorder characterized by recurrent attacks of cutaneous and submucosal swelling. In spite of the advances made in terms of pathophysiology, underlying mechanisms are
Ana López, Diego Fernández Romero
doaj   +1 more source

Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases [PDF]

open access: yes, 2014
Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions ...
Björkqvist, Jenny
core   +1 more source

[Hereditary angioedema].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989
Hereditary angioedema is a rare disease, transmitted as an autosomal dominant trait. The disease usually manifests as acute subcutaneous or submucosal swellings and abdominal pain of two to five days duration. When localized to head or throat, life-threatening edema of the larynx may occur. The disease is caused by reduced amount of active C1 inhibitor.
A, Sabbah, I, Marsollier, V, Trouillard
  +6 more sources

Successful C1 inhibitor short-term prophylaxis during redo mitral valve replacement in a patient with hereditary angioedema

open access: yesJournal of Cardiothoracic Surgery, 2010
Hereditary angioedema is characterized by sudden episodes of nonpitting edema that cause discomfort and pain. Typically the extremities, genitalia, trunk, gastrointestinal tract, face, and larynx are affected by attacks of swelling.
Coleman Suzanne   +2 more
doaj   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema

open access: yesAllergy, Asthma & Clinical Immunology, 2010
Background We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art ...
Bowen Tom   +59 more
doaj   +1 more source

Bradykinin-Mediated Angioedema Induced by Commonly Used Cardiovascular Drugs

open access: yesDrugs and Drug Candidates, 2023
ACE inhibitors, sartans, and sacubitril are among the most important drugs for the prevention of cardiovascular mortality and morbidity. At the same time, they are known to cause non-allergic bradykinin-mediated angioedema, a potentially fatal swelling ...
Janina Hahn   +3 more
doaj   +1 more source

Effect of cow's milk protein allergy during infancy on eating behavior at 4 years of age: A cohort study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives This study aimed to investigate the eating behaviors of preschool children who had been exposed to a restricted diet due to an oral food challenge‐confirmed diagnosis of cow's milk protein allergy (CMPA) during early infancy. Methods This prospective cohort study compared the eating behaviors of Brazilian children previously ...
Anne Jardim‐Botelho   +7 more
wiley   +1 more source

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