Results 61 to 70 of about 111,576 (246)

Impact of Chronic Urticaria on Major Life‐Changing Decisions: Greater Burden in Social, Physical, and Job/Career Domains

JEADV Clinical Practice, EarlyView.
The 32‐item Major Life‐Changing Decision Profile was validated and applied to 111 Turkish‐speaking chronic urticaria patients. Overall, 79.3% reported at least one affected major life‐changing decision, most commonly in social (69.4%), physical (56.8%) and job/career (36.9%) domains. Higher impact was observed in patients with disease onset ≤ 45 years (
Sinem Ornek Ozdemir, Kubra Cure, Defne Baskurt, Rabia Oztas Kara, Muhammed Burak Yucel, Esra Sarac, Pelin Kuteyla Can, Bahar Sevimli Dikicier, Ragip Ertas, Andac Salman, Murat Türk, Utkan Kızıltac, Faraz Mahmood Ali, Sam Salek, Andrew Y. Finlay, Emek Kocaturk   +15 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To identify clinical factors associated with laryngeal involvement in patients with angioedema and to validate a triage algorithm for determining the need for nasopharyngoscopic evaluation in the emergency department (ED). Study Design A retrospective review was performed of all patients presenting to the ED with angioedema or ...
Dan Yaniv, Igor Vainer, Dean Dudkiewicz, Aviram Mizrachi, Yaniv Hamzani, Eyal Yosefof, Nadav Granat, Gideon Bachar   +7 more
wiley   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Transitioning Patients From Second- to First-Line Prophylaxis in Hereditary Angioedema [PDF]

Modern targeted prophylaxis is recommended for patients with hereditary angioedema (HAE), but many remain on attenuated androgens.
Caroline E Cross
core   +1 more source

Real‐World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post‐Marketing Surveillance in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Hereditary angioedema (HAE) is a rare, autosomal dominant, life‐threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1‐inhibitor (C1‐INH) plasma protein are associated with HAE‐C1INH.
Kumiko Hosono, Miyako Hoshino
wiley   +1 more source

Art v 1 and Amb a 4 Co‐Sensitization Identifies Italian Patients at Risk for Mugwort‐Celery‐Spice Syndrome

Allergy, EarlyView.
Three molecular profiles identified among Art v 1/Amb a 4‐sensitized patients: Art v 1 monosensitization, Amb a 4 monosensitization, and dual sensitization to both allergens. Art v 1 monosensitization was predominantly associated with allergic rhinitis, reflecting a classical airborne allergy pattern.
Enrico Scala, Gabriella Cusa, Valeria Villella, Damiano Abeni, Mauro Giani, Emma Cristina Guerra, Maria Locanto, Giorgia Meneguzzi, Lia Pirrotta, Donato Quaratino, Alessandra Zaffiro, Elisabetta Caprini, Maria Barrale, Ignazio Brusca, Valerio Pravettoni, Lorenzo Cecchi, Danilo Villalta, Martina Aumayr, Irene Mittermann, Christian Lupinek, Riccardo Asero   +20 more
wiley   +1 more source

Maternal Prebiotic Supplementation Modifies Associations Between Intrapartum Antibiotics and Infant Allergy

Allergy, EarlyView.
This study examined whether antibiotic use altered the risk of infant allergic disease within a maternal prebiotics supplementation trial. Intrapartum antibiotics were maternal antibiotics administered during childbirth, from the onset of labour or induction until 1‐h before delivery.
Summer V. M. Walker, Thomas R. Sullivan, Rachelle A. Pretorius, Nina D'Vaz, Johnny Lo, Johan Garssen, Jeffrey A. Keelan, Desiree Silva, Susan L. Prescott, Claus T. Christophersen, Debra J. Palmer   +10 more
wiley   +1 more source

Ecallantide is a novel treatment for attacks of hereditary angioedema due to C1 inhibitor deficiency

, 2011
Henriette Farkas, Lilian Varga3rd Department of Internal Medicine, Semmelweis University, Budapest, HungaryAbstract: Hereditary angioedema (HAE) resulting from the deficiency of the C1 inhibitor protein is a rare disease, characterized by paroxysms of ...
null Varga, Henriette Farkas, Farkas H, Varga L   +3 more
core   +1 more source