Results 221 to 230 of about 305,201 (264)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Parental liver disease mortality is associated with unfavorable outcomes in patients with alcohol-associated hepatitis. [PDF]

Hepatol Commun
Tu W, Gawrieh S, Nephew L, McClain C, Tang Q, Dasarathy S, Vatsalya V, Simonetto DA, Kettler C, Szabo G, Barton B, Yu Y, Kamath PS, Sanyal AJ, Nagy L, Mitchell MC, Liangpunsakul S, Shah VH, Chalasani N, Bataller R, AlcHepNet Investigators.   +20 more
europepmc   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Reductions in medical visits and hospitalizations following berotralstat initiation in patients with hereditary angioedema in the United States. [PDF]

J Manag Care Spec Pharm
Christiansen SC, Lopez-Gonzalez L, MacKnight SD, Laliberté F, Spencer C, Boudreau J, Nestler-Parr S, Johnston DT, Gillard P, Zuraw BL.   +9 more
europepmc   +1 more source

Risk Factors Associated With Leber Hereditary Optic Neuropathy due to Rare Mutations in Mitochondrial DNA-Encoded Respiratory Complex I Subunits. [PDF]

Clin Genet
Bayona-Bafaluy P, Sanz-Pons J, Esteban O, Bueno-Borghi L, Ruiz-Pesini E.   +4 more
europepmc   +1 more source

Use of NCCN distress thermometer in cancer genetics patients. [PDF]

Support Care Cancer
Kennedy AM, Murad AM, Koeppe ES, Riba MB, Stoffel EM, Jacobs MF.   +5 more
europepmc   +1 more source

Genomic analysis revealing Lynch syndrome in a case of high-grade glioma: illustrative case. [PDF]

J Neurosurg Case Lessons
Koizumi S, Iwaizumi M, Baba S, Ushiama M, Hirata M, Kurozumi K.   +5 more
europepmc   +1 more source

Current Strategies for Managing Pheochromocytoma and Paraganglioma in Children and Adolescents. [PDF]

Med Sci Monit
Michalczewska A, Ambroziak U, Skrzypczyk P.   +2 more
europepmc   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus. [PDF]

Int J Cancer
Civita P, Mazzanti CM, Lessi F, Marchiò C, Scatena C, Menicagli M, Ghilli M, Roncella M, Naccarato AG, Sapino A, Hochman J, Pistello M, Bevilacqua G.   +12 more
europepmc   +1 more source

Strategies to Assess Risk for Hereditary Cancer in Primary Care Clinics: A Cluster Randomized Clinical Trial.

JAMA Netw Open
Swisher EM, Harris HM, Knerr S, Theoryn TN, Norquist BM, Brant J, Shirts BH, Beers F, Cameron D, Dusic EJ, Riemann LA, Devine B, Raff ML, Kadel R, Cabral HJ, Wang C.   +15 more
europepmc   +1 more source