Results 61 to 70 of about 3,517 (179)

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

Food Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan, Yau‐Yuen Chan, Guang Chen, Lin Xu, Cheng Zhang, Guoyi Tang, Yibin Feng, Ning Wang   +7 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Iranome: A catalogue of genomic variations in the Iranian population

, 2019
Considering the application of human genome variation databases in precision medicine, population-specific genome projects are continuously being developed. However, the Middle Eastern population is underrepresented in current databases.
Akbari, M., Amini, A., Arzhangi, S., Bagherzadeh, M., Beheshtian, M., Börno, S., Davarnia, B., Fattahi, Z., Haghdoost, A., Jalalvand, K., Jamali, P., Kahrizi, K., Khorram Khorshid, H., Malekzadeh, R., Mohammadi, Z., Mohammadzadeh, A., Mohseni, M., Najafipour, R., Najmabadi, H., Nejatizadeh, A., Nezhadi, S., Nikuei, P., Oladnabi, M., Poustchi, H., Sellars, E., Shamsi‐Gooshki, E., Shekari, M., Timmermann, B., Zohrehvand, E.   +28 more
core   +1 more source

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

Open-Label Taste-Testing Study to Evaluate the Acceptability of Both Strawberry-Flavored and Orange-Flavored Amylmetacresol/2,4-Dichlorobenzyl Alcohol Throat Lozenges in Healthy Children [PDF]

, 2013
BACKGROUND: Acute sore throat (pharyngitis) is one of the most common illnesses for which children are seen by primary care physicians. Most cases are caused by viruses and are benign and self-limiting. Clinically proven, over-the-counter throat lozenges
Adrian Shephard, Alex Thompson, Emma Field, Sandie Reader   +3 more
core   +1 more source

Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Health impacts of honey. ABSTRACT Honey is a natural and nutritious product of the honey bee (Apis mellifera) with low water content. Its color ranges from white to amber, with taste varying accordingly. The chemical form and viscosity of honey depend on its composition.
Ecem Bolat, Ahmet Alperen Canbolat, Sümeyye Sarıtaş, Mauro Lombardo, Anna Maria Witkowska, Hesham El‐Seedi, Mikhael Bechelany, Sercan Karav   +7 more
wiley   +1 more source

Advantages and pitfalls of an extended gene panel for investigating complex neurometabolic phenotypes [PDF]

, 2016
Neurometabolic disorders are markedly heterogeneous, both clinically and genetically, and are characterized by variable neurological dysfunction accompanied by suggestive neuroimaging or biochemical abnormalities.
Abulhoul, L, Anderson, G, Beesley, C, Boustred, C, Broomfield, A, Clayton, PT, Cleary, M, Drury, S, Gissen, P, Grunewald, S, Jacques, TS, Lench, N, Mills, PB, Papandreou, A, Rahman, S, Reid, ES, Varadkar, SM, Wedatilake, Y, Yue, WW   +18 more
core   +2 more sources

Lactational Western‐Style Fat Exposure in Mice Programs Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Male Offspring

Molecular Nutrition &Food Research, Volume 70, Issue 8, 27 April 2026.
Among the offspring fed with a high fat diet from 12 to 24 weeks of age, those that were exposed to a Western‐style fat diet during lactation had higher body weights, fat mass, insulin resistance, liver weights, and liver fat accumulation compared to a control diet, indicating increased susceptibility to MASLD. ABSTRACT Metabolic dysfunction‐associated
Amy Y. Zhao, Haijing Sun, Leyi Yan, Oyewale Shiyanbola, Dave Bridges, Brigid Gregg   +5 more
wiley   +1 more source

Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase) [PDF]

, 2017
Essential fructosuria is one of the oldest known inborn errors of metabolism. It is a benign condition which is believed to result from deficiency of hepatic fructokinase (ketohexokinase, KHK, E.C.2.7.1.3).
Bonthron, David T., Brady, Nlcola, Donaldson, lain A., Steinmann, Beat   +3 more
core  

The early history of medical genetics in Canada [PDF]

, 2004
This article shows that the intellectual and specialist movements that supported the growth of medical genetics in Canada between 1947 and 1990 were emergent phenomena, created, split, and reattached to different groups of actors, and reconfigured ...
Leeming, William
core   +1 more source