Results 21 to 30 of about 198,942 (291)

Case Report: Secukinumab for the treatment of severe psoriasis in a patient with hereditary hemochromatosis [PDF]

Frontiers in Medicine
There are several comorbidities associated with psoriasis, including genetic disorders such as hereditary hemochromatosis, which can lead to organ damage secondary to iron overload.
Yingzhe Yu, Lingyi Lu, Xin Fan, Sihan Wang, Bingjiang Lin   +4 more
doaj   +2 more sources

The contribution of diet and genotype to iron status in women:a classical twin study [PDF]

, 2013
This is the first published report examining the combined effect of diet and genotype on body iron content using a classical twin study design. The aim of this study was to determine the relative contribution of genetic and environmental factors in ...
Alexander J. Macgregor, AM Minihane, Ana M. Valdes, Ana Paula Arez, Anna A. Wawer, B Benyamin, B Lonnerdal, B Teucher, BA Thompson, CE McLaren, D Gaitán, G Rybo, Geoffrey R. Guile, Jane Skinner, JB Whitfield, JB Whitfield, JD Cook, JN Feder, K Oexle, L Almasy, L Hallberg, LJ Harvey, OM Visscher, R Hurrell, Rachel Hurst, SA Bingham, SJ Thorpe, Susan J. Fairweather-Tait   +27 more
core   +16 more sources

Case report: A rare case of hereditary hemochromatosis caused by a mutation in the HAMP gene in Fuyang, China [PDF]

Frontiers in Medicine
Hemochromatosis, also known as siderosis, is a disease caused by excessive iron deposition in human organs and tissues, resulting from iron metabolism disorders.
Jinling Wang, Jing Xu, Ning Jiang, Hui Liu, Fengcheng Li, Beibei Wang, Jin Wang, Ziyu Chu, Lin Tan, Shasha Li   +9 more
doaj   +2 more sources

Hemochromatosis: Hereditary hemochromatosis and HFE gene

Vitamins and hormones, 2019
Hereditary Hemochromatosis (HH) is an autosomal recessive genetic disease, characterized by an excessively increased absorption of dietary iron. Excess iron can be accumulated because of the lack of an effective excretory mechanism leading to toxic effects. HH is one of the most common genetic disorders in individuals of European descent.
Katsarou, M.-S., Papasavva, M., Latsi, R., Drakoulis, N.   +3 more
openaire   +4 more sources

New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia

Haematologica, 2019
Genetic iron-overload disorders, mainly hereditary hemochromatosis and untransfused β-thalassemia, affect a large population worldwide. The primary etiology of iron overload in these diseases is insufficient production of hepcidin by the liver, leading ...
Jing Liu, Wei Liu, Yin Liu, Yang Miao, Yifan Guo, Haoyang Song, Fudi Wang, Hongyu Zhou, Tomas Ganz, Bing Yan, Sijin Liu   +10 more
doaj   +2 more sources

Severe osteoporosis as atypical presentation of hereditary hemochromatosis [PDF]

Clinical Case Reports, 2022
Besides important metabolic repercussions, iron overload is reported to be associated with deleterious effects on articulations and bones. We present the case of a male patient diagnosed with severe osteoporosis and vertebral fracture, in whom the ...
Georgiana Cristina Taujan, Laura Iconaru, Mihaela Rosu, Olga Ana Kosmopoulou, Ioana Blerta Papadopoulou, Felicia Baleanu   +5 more
doaj   +2 more sources

Late-onset Hemochromatosis: Co-inheritance of β-thalassemia and Hereditary Hemochromatosis in a Chinese Family: A Case Report and Epidemiological Analysis of Diverse Populations

Internal medicine, 2017
Hereditary hemochromatosis and β-thalassemia can both result in the inappropriately low production of the hormone hepcidin, which leads to an increase in intestinal absorption and excessive iron deposition in the parenchymal cells.
Jinjun Yang, Y. Lun, X. Shuai, Ting Liu, Yu Wu   +4 more
semanticscholar   +3 more sources

Study of total stimulated saliva flow and hyperpigmentation in the oral mucosa of patients diagnosed with hereditary hemochromatosis. Series of 25 cases [PDF]

, 2011
Objective: To study lesions in the oral cavity of patients with hereditary hemochromatosis and determine their association with iron overload. Study Design: We took a clinical history, examined the pigmentation of the oral mucosa, and measured total ...
del Castillo Rueda, Alejandro, González García, Vanesa, Sánchez Pablo, Miguel Angel   +2 more
core   +2 more sources

[Hereditary Hemochromatosis]. [PDF]

Acta Gastroenterol Latinoam, 2023
Yamasato F, Daruich J.
europepmc   +2 more sources

Iron Metabolism in the Disorders of Heme Biosynthesis

Metabolites, 2022
Given its remarkable property to easily switch between different oxidative states, iron is essential in countless cellular functions which involve redox reactions. At the same time, uncontrolled interactions between iron and its surrounding milieu may be
Andrea Ricci, Giada Di Betto, Elisa Bergamini, Elena Buzzetti, Elena Corradini, Paolo Ventura   +5 more
doaj   +1 more source