Results 31 to 40 of about 192,458 (292)
Acta Marisiensis - Seria Medica, 2022 Objective: Hereditary hemochromatosis, or primary hemochromatosis, is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and ...
Sigmirean Victor
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New Mutations in HFE2 and TFR2 Genes Causing Non HFE-Related Hereditary Hemochromatosis
Genes, 2021 Hereditary hemochromatosis (HH) is an iron metabolism disease clinically characterized by excessive iron deposition in parenchymal organs such as liver, heart, pancreas, and joints. It is caused by mutations in at least five different genes.
G. Hernández +17 more
semanticscholar +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran +17 more
wiley +1 more source
Hemochromatosis - modern condition of the problem [PDF]
Терапевтический архив, 2018 The iron overload syndrome can be associated with various acquired states and hereditary factors. Hereditary hemochromatosis is the most common genetic disorder. Without therapeutic intervention the disease can lead to the development of life-threatening
N B Voloshina +3 more
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Liver Transplantation, EarlyView., 2022 Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala +6 more
wiley +1 more source
SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis [PDF]
Cell Metabolism, 2015 Supak Jenkitkasemwong +9 more
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Journal of Medical Case Reports, 2020 Introduction Hereditary hemochromatosis is an inherited disorder of iron metabolism, characterized by excessive iron deposition in major organs of the body, leading to multi-organ dysfunction. It is a genetically heterogeneous disease caused by mutations
Wasanthi Wickramasinghe +3 more
doaj +1 more source
Penetrance in hereditary hemochromatosis [PDF]
Blood, 2003 Ajioka and Kushner[1][1] make the point that ascertainment bias is the reason for the finding of low clinical penetrance in some studies of the incidence of hemochromatosis. They explain how they have avoided ascertainment bias in their study of hemochromatosis families by studying ...
Anne McCune, Mark Worwood
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Systematic Review of the Clinical Outcomes of Iron Reduction in Hereditary Hemochromatosis
Hepatology, 2020 Hereditary Hemochromatosis is a condition caused by defects in iron-sensing genes leading to parenchymal iron loading. If diagnosed early and treated appropriately, many of the complications, including liver fibrosis, cirrhosis and liver cancer ...
A. Prabhu +3 more
semanticscholar +1 more source