Results 51 to 60 of about 192,379 (224)

Disseminated cryptococcosis and hemochromatosis: clues to diagnosis

Autopsy and Case Reports, 2021
Hepatic cirrhosis, diabetes mellitus and iron overload can each independently predispose to cryptococcosis. Hereditary hemochromatosis leads to all three of these predispositions.
Larry Nichols, Lindsey Rowley, Ashley Lall   +2 more
doaj  

Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants

The journals of gerontology. Series A, Biological sciences and medical sciences, 2019
Background Iron is essential for life but contributes to oxidative damage. In Northern-European ancestry populations, HFE gene C282Y mutations are relatively common (0.3%–0.6% rare homozygote prevalence) and associated with excessive iron absorption ...
Jone Tamosauskaite, J. Atkins, L. Pilling, Chia-Ling Kuo, G. Kuchel, L. Ferrucci, D. Melzer   +6 more
semanticscholar   +1 more source

Fatores precipitantes na porfiria cutânea tardia no Brasil com ênfase\ud nas mutações do gene (HFE) da hemocromatose. Estudo de 60 casos [PDF]

, 2013
BACKGROUND:\ud Porphyria cutanea tarda is the most common form of porphyria, characterized by the decreased activity of the uroporphyrinogen decarboxylase enzyme.
Abrantes-Lemos, Clarice Pires, Cançado, Eduardo Luiz Rachid, Nakhle, Maria Cristina, Reis, Vitor Manoel Silva dos, Vieira, Fatima Mendonça Jorge   +4 more
core   +1 more source

Hereditary hemochromatosis: pathogenesis, symptoms, diagnosis and current treatment - literature review

Journal of Education, Health and Sport
Introduction: Hereditary hemochromatosis is the most common genetic disorder in Northern Europe. It involves an overload of iron in the tissues due to a deficiency of the protein hepcidin.
Dominika Prystacka-Szar, Natalia Rulewska, Filip Grabowski, Jakub Siemko, Dagmara Neska , Justyna Stadler-Szajda, Adrianna Czyżnikiewicz, Wenancjusz Stołowski, Magdalena Bujak, Magdalena Waśniowska   +9 more
doaj   +1 more source

Small Molecule Inhibitors of NFkB Reverse Iron Overload and Hepcidin Deregulation in a Zebrafish Model for Hereditary Hemochromatosis Type 3.

ACS Chemical Biology, 2018
Hereditary hemochromatosis (HH) is one of the most common genetic disorders in Caucasian populations, with no viable therapeutic options except phlebotomy.
Sandeep Basu, Kanika Jalodia, Shashi Ranjan, J. Yeh, R. Peterson, Chetana Sachidanandan   +5 more
semanticscholar   +1 more source

Iron overload and immunity [PDF]

, 2007
World J Gastroenterol. 2007 Sep 21;13(35):4707-15. Iron overload and immunity. Porto G, De Sousa M. Institute of Molecular and Cellular Biology, Rua do Campo Alegre, Porto 8234150, Portugal.
De Sousa, M., Porto, G.
core   +1 more source

Pathophysiological consequences and benefits of HFE mutations: 20 years of research

Haematologica, 2017
Mutations in the HFE (hemochromatosis) gene cause hereditary hemochromatosis, an iron overload disorder that is hallmarked by excessive accumulation of iron in parenchymal organs. The HFE mutation p.Cys282Tyr is pathologically most relevant and occurs in
Ina Hollerer, André Bachmann, Martina U. Muckenthaler   +2 more
doaj   +1 more source

Discrepancy between Serum Ferritin and Liver Iron Concentration in a Patient with Hereditary Hemochromatosis – The Value of T2* MRI

Case Reports in Oncology, 2020
Primary hemochromatosis is an inherited disorder, and the homeostatic iron regulator (HFE) gene C282Y mutation is a common cause of hemochromatosis in Europe. We are reporting a case of a 56-year-old female known to have hemochromatosis with the HFE gene
Mustafa A. Al-Tikrity, Mohamed A. Yassin
doaj   +1 more source

Non-HFE haemochromatosis [PDF]

, 2007
Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene.
Subramaniam, V. Nathan, Wallace, Daniel F.   +1 more
core   +2 more sources

Juvenile Hemochromatosis: Rheumatic Manifestations of 2 Sisters Responding to Deferasirox Treatment. A Case Series and Literature Review

Open Access Rheumatology: Research and Reviews, 2021
Jubran Alqanatish,1– 3 Banan Alsowailmi,1 Haneen Alfarhan,1 Albandari Alhamzah,1 Talal Alharbi1,2,4 1King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh 14611, Saudi Arabia; 2King Abdullah International Medical Research Center (
Alqanatish J, Alsowailmi B, Alfarhan H, Alhamzah A, Alharbi T   +4 more
doaj