Results 81 to 90 of about 10,302 (227)
Single‐Breathhold 3D MR Elastography in the Liver, With Simultaneous R2* and PDFF Mapping
Purpose To develop a sequence for the rapid acquisition of MR elastography (MRE) parameters in 3D, with simultaneous measurement of proton‐density fat fraction (PDFF) and R2* for multiparametric assessment of liver disease. Methods The proposed sequence uses an interleaved motion‐encoding scheme to acquire 3D volumes of all motion encodings and wave ...
Donovan P. Tripp +10 more
wiley +1 more source
A study of zinc transporter 1 and its role in Type 3 Haemochromatosis
Hereditary haemochromatosis is an autosomal recessive disorder of iron metabolism, characterised by increased iron absorption and progressive iron accumulation particularly in the liver.
Parkinson, Liza
core
ABSTRACT Background Three‐dimensional (3D) MR elastography (MRE) derives viscoelastic parameters that may reflect inflammation, but their frequency dependence and the influence of steatosis on inflammation grading and fibrosis staging remain unclear. Purpose To investigate 3D multifrequency MRE for assessing hepatic inflammation, fibrosis stage across ...
Shan Cai +11 more
wiley +1 more source
ABSTRACT Aims Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of cirrhosis. NIS2+ is a recently approved serum‐based test combining two biomarkers (miR‐34a‐5p and YKL‐40) to identify at‐risk MASH (i.e., MASH and significant fibrosis). Objective To assess the prevalence of at‐risk MASH by NIS2+ in individuals from primary care
Srilaxmi Kalavalapalli +12 more
wiley +1 more source
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell +3 more
wiley +1 more source
Should we use proton pump inhibitors as an add-on treatment in hereditary hemochromatosis?
Cite this article as: Kani HT, Gündüz F. Should we use proton pump inhibitors as an add-on treatment in hereditary hemochromatosis? Turk J Gastroenterol 2018; 29: 254-5.
Haluk Tarık Kani, Feyza Gündüz
doaj +1 more source
Unusual Colonic Iron Deposition Following Prophylactic Supplementation in an Infant: A Case Report
ABSTRACT Iron plays a vital role in physiological functions, and its deposition is typically limited to reticuloendothelial tissues in the presence of excess levels. We report a rare case of colonic iron deposition in a 13‐month‐old child without iron overload or toxicity. Despite a normal serum iron profile and administration of only prophylactic iron
Farid Imanzadeh +4 more
wiley +1 more source
Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging
ABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Nakul Ganju +5 more
wiley +1 more source
Hereditary hemochromatosis masquerading as rheumatoid arthritis
Early erroneous diagnosis of rheumatic disease is common in subjects with arthropathy due to hereditary hemochromatosis. A 71-year-old male with chronic obstructive pulmonary disease and monoclonal gammopathy underwent hip replacement and was referred to
NERI P +3 more
core

