Results 81 to 90 of about 113,339 (205)
Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL
Immunology, Volume 179, Issue 1, Page 149-160, September 2026.In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten +9 more
wiley +1 more source
Diagnosis of hereditary hemochromatosis in the era of genetic testing
, 2012 Background Homozygous C282Y mutation in HFE gene is responsible for the majority of hereditary hemochromatosis cases. Since 1996 this mutation can be identified by a simple genetic test.
Stuhrmann, Manfred +6 more
core +1 more source
Journal of Gastroenterology and Hepatology, Volume 41, Issue 9, Page 2639-2655, September 2026.ABSTRACT Background Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer‐related deaths in Malaysia. Early detection increases the likelihood of curative treatment and improves survival. This consensus document aims to provide evidence‐based, locally relevant recommendations for the prevention and early detection of HCC.
Su Yin Lau +18 more
wiley +1 more source
, 2012 Hereditary hemochromatosis is characterized by tissue iron loading and associated organ damage. However, the phenotype can be highly variable. The relationship between iron loading of different organs and the temporal nature of its deposition is still ...
Wallace, D.F. +13 more
core +1 more source
Hereditary Hemochromatosis and Iron Overload Disorders: A Clinical Review
, 2021 Iron is an essential micronutrient and a critical component of oxygen transport, numerous metabolic enzymes, and reaction centers of redox enzymes. Elevated iron can lead to iron accumulation in parenchymal organs, which can result in cardiac symptoms ...
Oliver, Deanna
core +1 more source
Marcadores genéticos do MHC-Classe I na esteatohepatite não alcoólica [PDF]
, 2009 Mestrado em Biologia Molecular e CelularO Fígado é o principal órgão regulador do metabolismo do ferro. Distúrbios relacionados com a sobrecarga de ferro podem ser devido a factores genéticos, como na HH com mutações conhecidas para o gene HFE, mas ...
Costa, Mónica Isabel Encarnação
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Diagnostic evaluation of hereditary hemochromatosis (HFE and non-HFE).
, 2014 International audienceThe management and understanding of hereditary hemochromatosis have evolved with recent advances in iron biology and the associated discovery of numerous genes involved in iron metabolism.
Brissot, Pierre, Bardou-Jacquet, Edouard
core +1 more source
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 2004 The case of a 43-year-old male is presented, with diagnosed diabetes mellitus,heart failure, skin pigmentation, hepatic cirhosis, and hereditary hemochromatosis confirmed by liver biopsy. The objective of this publication is to have hemochromatosis in mind as a differential diagnosis in a middle-aged patient with several pathologies and organs involved.
Lidia, Landa Garrido +4 more
openaire +3 more sources
Should we use proton pump inhibitors as an add-on treatment in hereditary hemochromatosis?
The Turkish Journal of Gastroenterology, 2018 Cite this article as: Kani HT, Gündüz F. Should we use proton pump inhibitors as an add-on treatment in hereditary hemochromatosis? Turk J Gastroenterol 2018; 29: 254-5.
Haluk Tarık Kani, Feyza Gündüz
doaj +1 more source
Hereditary hemochromatosis masquerading as rheumatoid arthritis
, 2001 Early erroneous diagnosis of rheumatic disease is common in subjects with arthropathy due to hereditary hemochromatosis. A 71-year-old male with chronic obstructive pulmonary disease and monoclonal gammopathy underwent hip replacement and was referred to
NERI P +3 more
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