Results 111 to 120 of about 91,892 (256)
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, EarlyView.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature
Clinical Pharmacology &Therapeutics, EarlyView.The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory +13 more
wiley +1 more source
Популяционный и генетический анализ пищевых предпочтений среди жителей Украины
Фактори експериментальної еволюції організмів, 2015 Aims. The aim of the study was to perform population analysis of food preferences for sweets, meat, fruit, salty food, the first vegetable dishes, fastfood and fatty food among young people in a sample of Ukraine as well as to evaluate heritability of ...
И. А. Тимошина +2 more
doaj
Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology
Developmental Dynamics, EarlyView.Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley +1 more source
Psychiatric Morbidity Is Overrepresented in Young Girls at High Risk of Developing Anorexia Nervosa
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Psychiatric comorbidity frequently presents in anorexia nervosa (AN). Yet, the premorbid mental health status is relatively unknown. The aim of this study was to map out psychiatric morbidity and psychopathology among girls at familial high risk (FHR) of developing AN, thereby detecting possible underlying vulnerabilities preceding ...
Karin Dahlin +3 more
wiley +1 more source
Ecography, EarlyView.Global change is reshaping the distribution of biodiversity and the functioning of ecosystems. Predicting the long‐term consequences of such changes remains a challenge due to a need for a clear understanding of the mechanisms underpinning ecosystem‐level responses, as well as the role of geographical and environmental contingencies.
Miguel G. Matias +15 more
wiley +1 more source
Grassland Research, EarlyView.There is genetic variation in ryegrass for the ability to respond to nitrogen fertilizer, Breeding nitrogen use efficient cultivars can increase farm profitability and sustainability. Abstract Background Improving the nitrogen use efficiency (NUE) of pastures has the benefit of reducing costs of production and reducing nitrogen loss to the environment.
Junping Wang +6 more
wiley +1 more source
Roles of histone lysine methylation in neurodevelopment and related disorders
Ibrain, EarlyView.This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen +3 more
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source