Results 101 to 110 of about 152,085 (301)

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri   +6 more
wiley   +1 more source

The heritability of implicit self-esteem: A twin study

open access: yes, 2017
In a twin sample (117 monozygotic and 115 dizygotic twin pairs), we assessed implicit self-esteem by using the implicit association test (IAT). Results showed that implicit self-esteem was heritable with substantial environmental influences.
Huajian Cai   +3 more
core   +1 more source

Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset [PDF]

open access: yes, 2009
Appendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood.
Nicholas Martin   +7 more
core   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle   +3 more
wiley   +1 more source

Measuring Child Disadvantage: Comparing Multidimensional and Socioeconomic Approaches for Predicting Developmental Outcomes

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong   +7 more
wiley   +1 more source

Genetic and Phenotypic Variability for Racing Performance of Trotter Horse in Serbia [PDF]

open access: yes, 2015
Horse race results in studbooks are supposed to give information to manage the selection of trotters based on the analysis of genetic and phenotypic parameters.
Trivunovic, S, Strbac, Lj
core  

The mystery of missing heritability: Genetic interactions create phantom heritability

open access: yes, 2011
Human genetics has been haunted by the mystery of “missing heritability” of common traits. Although studies have discovered >1,200 variants associated with common diseases and traits, these variants typically appear to explain only a minority of the ...
Sunyaev, Shamil R., Lander, Eric Steven
core   +1 more source

Heritability, reliability of genetic evaluations and response to selection in proportional hazard models [PDF]

open access: yes, 2002
The purposes of this study were 1) to investigate the heritability, reliability, and selection response for survival traits following a Weibull frailty proportional hazard model; and 2) to examine the relationship between genetic parameters from a ...
Ducrocq, V.   +3 more
core   +1 more source

Beyond Behaviour: Exploring How Positive Behaviour Support Might Work for Autistic Children Within Australia's NDIS

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Positive Behaviour Support (PBS) is the National Disability Insurance Scheme (NDIS) endorsed‐behavioural intervention framework. Understanding how and why PBS is effective is critical, given the increasing number of autistic children accessing the NDIS.
Cameron Stott   +4 more
wiley   +1 more source

Mapping the heritability of disease: a nationwide study

open access: yesNature Communications
Heritability estimates are essential for understanding genetic and environmental contributions to disease, yet large-scale studies remain scarce. In this study, we leverage the Danish national health registers, including medical records for more than 10 ...
Janne Auning   +4 more
doaj   +1 more source

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