Results 81 to 90 of about 236,259 (268)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source
BMC Bioinformatics, 2019 Background Data from genome-wide association studies (GWASs) have been used to estimate the heritability of human complex traits in recent years. Existing methods are based on the linear mixed model, with the assumption that the genetic effects are ...
Xin Li +7 more
doaj +1 more source
Are Attitudes Towards Economic Risk Heritable? Analyses Using the Australian Twin Study of Gambling [PDF]
This study employs multiple regression models based on DeFries and Fulker (1985), and a large sample of twins, to assess heritability in attitudes towards economic risk, and the extent to which this heritability differs between males and females ...
Le, Anh T. +3 more
core
Australian Journal of Social Issues, EarlyView.ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong +7 more
wiley +1 more source
Adaptability of safflower (Carthamus tinctorius L.) genotypes to some New Zealand environments : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Plant Science at Massey University [PDF]
, 1981 Seven safflower (Carthamus tinctorius L.) genotypes were grown at three sites (Massey, Aorangi and Flockhouse) in the Manawatu area in years 1978 and 1979. Three additional genotypes from the world germplasm collection were included in the study in 1979.
De Silva, Handunnethi Nihal
core
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Over one billion people worldwide suffer from obesity, and the number is continually rising. Animal models, especially mouse models, are crucial to identifying the genetic components of complex disorders and exploring the potential applications of these genetic findings.
Hanifa J. Abu‐Toamih Atamni +7 more
wiley +1 more source
Acta Agrobotanica, 2013 The object of the studies in 1977 was a population of 15 F1 hybrids, 11 F2 progenies and 16 parental forms (8 male-sterile A lines and 8 inbred C lines - Table 2).
Roch W. Doruchowski
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang +14 more
wiley +1 more source