Results 31 to 40 of about 204,479 (230)

Heritability of Malaria in Africa [PDF]

PLoS Medicine, 2005
While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown.We have used pedigree-based genetic variance component analysis to determine the relative contributions of genetic and other factors to the variability in incidence of malaria and other infectious
Margaret J. Mackinnon, Thomas N. Williams, Thomas N. Williams, Tabitha W. Mwangi, Robert W. Snow, Robert W. Snow, Kevin Marsh, Kevin Marsh   +7 more
openaire   +7 more sources

Heritability in friendship networks [PDF]

SSRN Electronic Journal, 2020
AbstractFriendship networks account for a large part of an individual’s economic success or failure in life. Using data from the German TwinLife study, we explore, within a classical twin design, to which extent friendship networks are related to genes.
Selen Yildirim, Selen Yildirim, Michael Neugart   +2 more
openaire   +3 more sources

Association between estrus and onset of seizures in dogs with idiopathic epilepsy [PDF]

, 2014
Background: Catamenial epilepsy in humans is defined as changes in seizure frequency over the course of the menstrual cycle. Three hormonally based patterns of seizure exacerbation have been determined.
Van Meervenne, Sofie, Volk, HA, Van Ham, Luc   +2 more
core   +2 more sources

Altered Brain‐Behavior Association During Resting State is a Potential Psychosis Risk Marker

Advanced Science, EarlyView.
The study detects a potential multimodal biomarker that can be promising for identifying early markers of psychosis. It shows a consistent brain‐behavior association between a circuit of interconnected regions and executive function in neurotypical controls and individuals at various stages of psychosis.
Leonardo Fazio, Giuseppe Stolfa, Roberta Passiatore, Angelantonio Tavella, Giuseppe Blasi, Madalina O. Buciuman, Aaron L. Goldman, Shalaila S. Haas, Lana Kambeitz‐Ilankovic, Nikolaos Koutsouleris, Monica Nicoli, Teresa Popolizio, Antonio Rampino, Anne Ruef, Fabio Sambataro, Pierluigi Selvaggi, William Ulrich, Daniel R. Weinberger, Apulian Network on Risk for Psychosis, PRONIA Consortium, Alessandro Bertolino, Linda A. Antonucci, Giulio Pergola   +22 more
wiley   +1 more source

Heritability of Personality [PDF]

Psihologijske teme, 2017
The aim of this study is to simplify the issue of the concept of heritability, to give an introduction to the behavioral genetic theory and methods, as well as to give an overview of the current knowledge about heritability of personality and the quantitative and molecular genetic approach to estimate heritability.
Denis Bratko, Ana Butković, Tena Vukasović Hlupić   +2 more
openaire   +5 more sources

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture. [PDF]

, 2019
SNP-heritability is a fundamental quantity in the study of complex traits. Recent studies have shown that existing methods to estimate genome-wide SNP-heritability can yield biases when their assumptions are violated.
Burch, Kathryn S, Hou, Kangcheng, Majumdar, Arunabha, Mancuso, Nicholas, Pasaniuc, Bogdan, Sankararaman, Sriram, Shi, Huwenbo, Wu, Yue   +7 more
core  

The Familial Clustering of Age at Menarche in Extended Twin Families [PDF]

, 2007
The timing of puberty is complex, possibly involving many genetic factors that may interact with environmental influences. Familial resemblance for age at menarche was studied in a sample of 4,995 female twins, 1,296 sisters, 2,946 mothers and 635 female
A Must, A Pickles, B Towne, CL Sisk, DB Pillemer, DI Boomsma, Dorret I. Boomsma, DS Falconer, DZ Loesch, EB Greif, FJP Ebling, FL Schmidt, G Willemsen, G Wyshak, J Kaprio, JH Stubbe, JL Jinks, JM Meyer, JM Vink, JR Koopmans, L Ibanez, L Zacharias, MR Palmert, SA Treloar, SM Berg van den, SR Ojeda, Stéphanie M. van den Berg   +26 more
core   +6 more sources

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Genetic variability and correlation analysis of rice (Oryza sativa L.) inbred lines based on agro-morphological traits [PDF]

, 2016
In order to evaluate genetic variability of agro-morphological traits and also determine the correlation between grain yield with its components in rice lines, 17 recombinants inbred lines, their parents and a check variety were grown in research station
Audebert, Alain, Kam, Honore, Konate, Abdourasmane K., Sanni, Ambaliou, Zongo, Adama   +4 more
core   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source